摘要
:[目的]研究子宫内膜间质肉瘤的诊断和治疗方法。[方法]对38例子宫内膜间质肉瘤进行回顾性分析 ,其中Ⅰ期13例 ,Ⅱ期14例 ,Ⅲ期7例 ,Ⅳ期4例 ,38例均经手术治疗。10例术后补充放疗 ,11例补充化疗 ,7例补充放疗加化疗。[结果]本组病例总的3年及5年生存率分别为54 3 %(19/35)及45 5%(15/33) ,Ⅰ期病例3年及5年生存率分别为76 9 %(10/13)及61 5%(8/13) ,Ⅱ期为50.0 %(7/14)及46 2 %(6/13)。[结论]子宫内膜间质肉瘤的预后和组织类型、临床分期、治疗方法密切有关 ,综合运用手术、放疗、化疗及孕激素治疗能减少阴道及盆腔复发 ,提高生存率。
To investigate the diagnosis and treatment of 38 endometrial stromal sarcoma.A total of 38 cases with endometrial stromal sarcoma were eligible for retrospective study.Thirteen cases were in stage Ⅰ,14 in stage Ⅱ,7 in stage Ⅲ,4 in stage Ⅳ. Thirty-eight cases were treated with surgery,among them,10 by surgery plus radiotherapy,11 by surgery plus chemotherapy,7 by surgery plus radiotherapy and chemotherapy.The overall 3-,5-year survival rate were 54.3% (19/35),45.5%(15/33)respectively.The 3-,5-year survival rate in stageⅠpatients were 76.9%(10/13),61.5%(8/13)and in stage Ⅱ were 50.0%(7/14),46.2%(6/13)respectively.[Conclusion]The prognosis of endometrial stromal sarcoma is closely related to histologic type,clinical stage,and treatment methods.It seems that combination of surgery,radiotherapy,chemotherapy and endocrinotherapy can reduce viginal and pelvic recurrence and raise survival rate.
关键词
子宫内膜间质肉瘤
诊断
治疗
endometrial stromal sarcoma
diagnosis
treatment
