摘要
目的 :探讨高原肺水肿患者血浆内皮素 -1、一氧化氮含量变化及意义 ;方法 :对急进高原患高原肺水肿患者进行治疗前、治愈后血浆中内皮素 -1和一氧化氮含量测定 ,并与急进高原的健康人作对照研究 ;结果 :高原肺水肿患者血浆中内皮素 -1和一氧化氮含量在治疗前显著高于治愈后和对照组 (P <0 .0 1 ) ,且临床治愈后高原肺水肿患者血浆中内皮素 -1及一氧化氮含量仍高于正常对照组 (P <0 .0 5 ) ;结论 :内皮素 -1和一氧化氮参与了高原肺水肿的疾病过程。
Objective:To study the changes of contents of plasma endothelin-1(ET-1)and nitric oxide(NO)in patients with high altitude pulmonary edema(HAPE).Methods:In the experiment,the contents of ET-1 and NO in the plasma were measured in 23 cases HAPE patients before and after clinical cure and 21 cases served as healthy control.Results:The level of ET-1 and NO were significantly increased in HAPE patients compared with those after clinical cure and the healthy controls (P<0.01),and the level of ET-1 and NO were higher in HAPE patients after clinical cure than the healthy controls (P<0.05).Conclusion:The results showed that ET-1 and NO participated the course of HAPE.
出处
《高原医学杂志》
CAS
2000年第4期1-3,共3页
Journal of High Altitude Medicine
关键词
高原肺水肿
内皮素
一氧化氮
测定
High altitude
Pulmonary edema
Endothelin
Nitric oxide
