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降钙素原临床研究进展 被引量：18

Meke progress on clinical applications of procalcitonin
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摘要 综述降钙素原(PCT)的生化特点、来源及其代谢、生物学效应、测定、检测方法、临床各科室的应用价值及对鉴别细菌或病毒性感染、判断感染的严重程度及预后的重要意义。 The procalcitonin （PCT） biochemical characteristics, origin and metabolism, biological effects, measuring, testing methods, clinical departments and the application value in differentiating bacterial or viral infection, to determine the severity of infection and prognosis significance.
作者 王智慧 祝啸先
机构地区 内蒙古科技大学包头医学院 内蒙古自治区妇幼保健院
出处 《疾病监测与控制》 2013年第11期680-683,共4页 Journal of Diseases Monitor and Control
关键词 降钙素原 检测方法 临床应用 细菌感染 脓毒症 炎症 procalcitonin detection methods clinical applications bacterial infection sepsis inflammation
分类号 R515.3 [医药卫生—内科学]
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参考文献18

  • 1Assicot M, Gendrel D, Carsin H, et a/.High serum procalcitonin concentrations in patients with sepsis and infection[J]. Lancet, 1993,341(8844):515-8.
  • 2Russwurm S, Wiederhold M, Oberhoffer M, et al. Molecular aspects and natural source of procalcitonin[J].Clin Chem Lab Med, 1999,37(8):789-97.
  • 3胡如雪.降钙素原(PCT)的临床应用价值[J].江西医学检验,2005,23(3):259-259. 被引量：39
  • 4Bohuon C.A brief history of proealcitonin[J].Intensive Care Med, 2000,26(Supp12):S146-?.
  • 5Fisher LA, Kikkawa DO, Rivier JE, et af. Stimulation of noradrenergic sympathetic outflow by ealcitonin gent-related peptide[J].Nature, 1983,305(5934):534-6.
  • 6Ghillani PP, Mott6 P, Troalen F, et a~ Identification and measurement of caleitonin precursors in serum of patients with malignant diseases[J].Cancer Res, 1989,49(23):6845-51.
  • 7Snider POJ Jr, Nylen ES, Becker ~L. procalcitonin and its component peptides in systemic inflammation: immunochemical cbaracterization[J].Investig ~ed, 1997,45(9):552-60.
  • 8Oberhoffer ~Vogelsang H,J~ger L, et aLKatacalcinand calcitonin immunoreactivity in different types of ]eukocytes indicate intracellular procalcitonin content [J].Crit Care, t999, 14(1):29-33.
  • 9Russwurm S, Wiederhold M, Oberhoffer M, et al. Procalcitonin as monocytic marker for early diagnosis in septic abortion [J].ZGeburtshilfe Neonatol, 2000,204(1):34-8.
  • 10Torb~ A, Czajka R. Procalcitonin in cervicovaginal secretion in pregnancies complicated by preterm labor-a preliminary report [J]. Eur J Obstet Gynecol Reprod Biol, 2004, 116(2):177-81.

二级参考文献8

  • 1Karzai W,Oberhoffer M, Meier - Helhnann A, et al. Procalcitonin - A new indicator of the systemic response to severe infections. Infection, 1997,25 (6) :329 - 341.
  • 2Assicot M, GendrelD, CarsinH, et al. High serumprocalcitonin concentrations in patients with sepsis and infection. Lancet,1993,341:515 -518.
  • 3Harbarth S, Holeckova K, Froidevaux C, et al. Diagnostic value of procalcitonin, 6 interleukin and interleukin 8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Car Med 2001, 164,396 - 402.
  • 4Casad F, Asensio J, Arranz E, et al. Serum procalcitonin in chilgren with suspected sepsis : Acomparison with C - reactive protein and neutrophil count. Pediatr Crit Care Med,2003,4 (2) : 190 - 195.
  • 5Bousseky N, Leroy O, Georges h, et al. Diagnostic values of admission procalcitonin levels in community acquired pneumonia in an intensive care unit. Infection, 2005,33 ( 4 ) : 257 - 263.
  • 6Castelli GP,Pognani C, Cita M, et al. procalcitonin , C - reactive protein, white blood cell and SOFA score in ICU:Diagnosis and monitoring of sepsis. Minerva anestesiol. Crit Care Med,2006,72( 1 ) :69 -80.
  • 7张瑾,赵诸慧,张灵恩.感染患儿血前降钙素水平的变化[J].国外医学（儿科学分册）,2000,27(1):7-9. 被引量：55
  • 8阴赪宏,王超,文艳,张淑文,王宝恩.降钙素原及其在脓毒症诊断中的应用[J].中华急诊医学杂志,2003,12(5):357-358. 被引量：40

共引文献57

同被引文献149

引证文献18

二级引证文献93

疾病监测与控制
2013年 第11期

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