摘要
目的:了解平顶山市矿区非酒精性脂肪肝(non-alcoholic fatty liver disease,NAFLD)患病率及其危险因素,为矿区NAFLD防治提供可能科学依据.方法:通过整群抽样的方法,抽取2012-06/2013-04在平顶山市矿区66个区队2299例地面工作人员进行NAFLD患病率调查,采用单因素和多因素Logistic回归分析非酒精性脂肪肝的相关危险因素.结果:(1)2299例工作人员NAFLD的患病率为22.48%(5 1 7/2 2 9 9),其中,男性患病率为31.12%(366/1176),女性患病率为13.41%(151/1123),男女患病率间差异有统计学意义(P<0.05);(2)多因素Logistic回归分析显示,腰围(OR=5.948)、体质量指数(body mass index,BMI)(OR=4.708)、高脂血症(OR=3.781)、高尿酸血症(OR=3.239)、高血糖(OR=2.363)、高血压(OR=1.976)、胆石症(OR=2.722)、肝功异常(OR=2.430)为平顶山矿区地面工作人员非酒精性脂肪肝的主要危险因素(P<0.05).结论:性别(男)、超质量、高脂血症、高尿酸血症、高血糖、高血压、胆石症、肝功异常可能是非酒精性脂肪肝发病的危险因素,应有针对性的进行干预.
AIM: To analyze the prevalence of and main risk factors for non-alcoholic fatty liver disease (NAFLD) in Pingdingshan city. METHODS: A total of 2299 participants were selected from 66 crew teams in Pingdingshan city by cluster random sampling. Question- naires were used to investigate the prevalence of NAFLD, and non-conditional Logistic regressionanalysis was used for analysis of risk factors for NAFLD. RESULTS: The overall prevalence of NAFLD was 22.48% (517/2299). The prevalence rate of NAFLD was significantly higher in males than in females [31.12% (366/1176) vs 13.41% (151/1123), P 〈 0.05]. Overweight (OR = 4.708), hyperlipid- emia (OR = 3.781), hyperuricemia (OR = 3.239), high blood sugar (OR = 2.363), hypertension (OR = 1.976), cholelith disease (OR = 2.722), and ab- normal hepatic function (OR = 2.430) were risk factors for NAFLD (all P 〈 0.05). CONCLUSION: Gender (male), overweight, hy- perlipidemia, hyperuricemia, high blood sugar, high blood pressure, cholelith disease, and ab- normal hepatic function are related to NAFLD. Targeted interventions are necessary to reduce and prevent the occurrence of NAFLD.
出处
《世界华人消化杂志》
CAS
北大核心
2013年第32期3561-3565,共5页
World Chinese Journal of Digestology
关键词
非酒精性脂肪肝
危险因素
患病率
Non-alcoholic fatty liver disease
Riskfactors
Prevalence