摘要
目的分析新生儿乙肝疫苗接种情况并探讨乙肝疫苗接种后对新生儿的保护作用。方法选取辖区内2012年1月到2013年6月出生的新生儿1 800名作为研究对象,对新生儿抽血进行"两对半"检查,并统计新生儿乙肝疫苗接种情况,接种完成后抽血检查新生儿乙肝病毒表面抗原及抗体情况,统计新生儿乙肝表面抗原阳性率及抗体保护率。以全程(三针)接种乙肝疫苗的新生儿为观察组,以人群为对照组,比较两组研究对象在乙肝表面抗原阳性率及抗体保护率之间的差异。结果新生儿乙肝疫苗接种情况非常理想,第一针及时接种率达到97.56%,全程及时接种率93.78%,全程接种率达到94.56%;新生儿HBs阳性率低于人群,且新生儿抗体保护率高达85.49%,高于人群抗体保护率,差异均具有统计学意义(P<0.05);疫苗接种后,不良反应少且症状轻微。结论乙肝疫苗切实发挥了对新生儿的保护作用,且安全可靠。
Objective To analyze the hepatitis B vaccination status in the newborn, and explore the protective effect of hepatitis 13 vaccination for newborns. Methods 1 800 newborns fi＇om January 2012 to June 2013 were selected as the research objects. All cases received the serological examination, and the hepatitis B vaccination statuses were summarized. The surface antigen positive rate and antibody protection rate of neonatal hepatitis B were summarized. Newborns with hepatitis B vaccine were selected as the observation group, and the population was selected as the control group. The surface antigen positive rate and antibody protection rate were compared between two groups. Results The rate of hepatitis B vaccination in the newborn was good. The rates of timely hepatitis B vaccination at first time was 97.56%. The rate of whole course and timely hepatitis B vaccination was 93.78%, and the whole course vaccination rate was 94.56%. The rate of riBs in the newborns was lower than that in the overall population. The antibody of protection in the newborn was 85.49%. After vaccination, there were fewer adverse reactions with mild symptoms. Conclusions It can get a satisfactory effect to use the hepatitis B vaccination in the newborns.
出处
《临床医学工程》
2013年第12期1604-1605,共2页
Clinical Medicine & Engineering
关键词
乙肝疫苗
疫苗接种
Hepatitis B vaccine
Vaccination
