摘要
目的 探讨支撑喉镜下CO2激光对早期声门型喉癌血清血管内皮生长因子（VEGF）和生活质量的影响.方法 将82例手术治疗的早期声门型喉癌患者随机分为两组,观察组36例,对照组46例,对照组采用传统手术治疗,观察组采用支撑喉镜下CO2激光治疗,术后随访6个月,比较患者的生活质量和血清VEGF水平.结果 两组患者治疗后血清VEGF水平均有明显降低,并且观察组比对照组降低更明显（P＜0.05）.两组术后6个月患者的生活质量评分均有明显升高,并且与对照组比较,观察组生活质量评分升高更明显（P＜0.05）.结论 支撑喉镜下CO2激光可以明显改善早期声门型喉癌患者的血清VEGF水平和生活质量.
Objective To study the effectiveness of laryngoscope CO2 laser on serum vascular endothelial growth factor（VEGF） and quality of life in patients with early glottic cancer.Methods Eighty-two patients with early glottic cancer were randomly divided into two groups,the observation group （36 cases） and the control group（46 cases）.The patients in the control group were operated through the conventional treatment,while the patients in the observation group were operated through laryngoscope CO2 laser.Their serum VEGF levels and quality of life were compared.Results Serum VEGF levels in both groups decreased after operation.Serum VEGF levels decreased more obviously in observation group （P ＜ 0.05）.Quality of life in both groups improved after six months for operation.Quality of life in the observation group was higher than that in the control group （P ＜ 0.05）.Conclusions Laryngoscope CO2 laser can significantly improve serum VEGF levels and quality of life in patients with early glottic cancer.
出处
《中国实用医刊》
2013年第24期89-91,共3页
Chinese Journal of Practical Medicine
关键词
喉癌
激光
血管内皮生长因子
生活质量
Glottic cancer
Laser
Vascular endothelial growth factor
Quality of life
