摘要
甘草浸膏的制备多采用水回流法，生产周期长，溶媒用量大，甘草酸收率低。本研究以含氨０．５％的１０％乙醇溶液作萃取剂，采用连续提取工艺，甘草酸收率可达１１％以上，较水回流法提高约８％，提取时间缩短近一半，液固比从１４：１降低至６：１，而且产品内在质量明显提高。
The producing procession of extractum glycyrrhizae usually adopts water reflux method. This procession needs a long period of production, a large quantity of solvents, and low rate of return of glycyrrhiric acid. In the paper,by using 10% alcohol solution with 0. 5 % ammonia as extraction solvent, and adopting continuous extraction technology,more than 11 % rate of return of glycyrrhizic acid can be attained,approximately 8 % higher than water reflux method, the extraction time can be nearly half shortened, and liquid solid ratio decreased from 14: 1 to 6: 1, and internal quality of products has been improved. The continuous extraction technology is that heated solvents in evaporator enter extractor in which temperature was controlled within 50- 55℃, when solvents in extractor reach some altitude. They return to evaporator again, maximum differential concentration of solid-liquid phase is constant.
出处
《天然产物研究与开发》
CAS
CSCD
1999年第6期40-43,共4页
Natural Product Research and Development
基金
山西省归国留学人员基金!941001
关键词
甘草浸膏
提取
水回流法
连续提取
Extractum glycyrrhizae, extract, water reflux method, continuous extraction
