摘要
目的探讨老年喉癌患者手术治疗效果及其影响因素。方法回顾性分析2008年1月至2013年1月收治的240例老年喉癌患者的临床资料。结果 240例患者的1、3、5年生存率分别为96.7%、70.4%和52.1%。单因素结果显示:肿瘤原发部位、淋巴结转移、肿瘤大小、TNM分期、病理分级、治疗方式、年龄对患者预后影响有统计学意义(P<0.05);多因素分析结果显示:肿瘤原发部位、TNM分期、淋巴结转移和治疗方式是影响喉癌预后的独立因素。结论影响喉癌预后的独立危险因素为肿瘤的原发部位、TNM分期、淋巴结转移情况以及手术方式。喉功能保全性手术是治疗老年喉癌的理想手术方式,早期诊断和治疗是提高生存率的关键。
Objective To investigate the surgical effect and its influence factors in senile patients with laryngeal cancer. Methods Clinical data of 240 senile patients with laryngeal cancer admitted to our hospital from January 2008 to January 2013 were retrospectively analyzed. Results The 1-,3- and 5-year survival rates were 96. 7% ,70.4% and 52. 1% respectively. Single factor results suggested that the primary site of tumor, lymph node metastasis, tumor size, TNM staging, pathological classification, treatment and age was statistically significant factors （P 〈 0. 05） ; Muhifactor analysis showed that the primary site of tumor, TNM staging, lymph node metastasis and treatment are the independent factors for prognosis of laryngeal cancer. Conclusions Primary site of tumor, TNM staging, lymph node metastasis status and operation method were independent risk factors of prognosis of laryngeal cancer. Laryngeal conservation surgery is ideal in the treatment of senile patients with laryngeal cancer. Early diagnosis and treatment are keys to improve survival rate.
出处
《中国肿瘤临床与康复》
2013年第11期1243-1245,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
耳鼻咽喉肿瘤
老年人
外科手术
影响因素
Qtorhinolaryngologic neoplasms
Aged
Surgical procedures, operative
Influence factor
