期刊文献+

阿卡波糖治疗2型糖尿病餐后低血糖的临床效果分析 被引量:6

下载PDF
导出
摘要 目的:探讨2型糖尿病餐后低血糖患者应用阿卡波糖治疗的临床效果。方法:选取2型糖尿病合并餐后低血糖患者128例为研究对象,随机将患者分为二甲双胍治疗组(对照组)64例以及阿卡波糖治疗组(观察组)64例,治疗4周后对比分析两组患者用药治疗前后餐后低血糖发生次数以及治疗前后患者空腹血糖值(FPG)及餐后2h血糖值(2hPBG)的变化,并观察两组患者不良反应反生情况。结果:治疗第1周观察组患者低血糖发生率低于对照组,但两组患者对比无统计学意义(P>0.05),治疗第2周后,观察组患者低血糖发生次数显著低于对照组,差异有统计学意义(P<0.05)。两组患者治疗后FPG以及2hPBG值较治疗前下降,差异有统计学意义(P<0.05),且观察组下降幅度大于对照组,差异有统计学意义(P<0.05)。观察组患者有4例患者出现腹泻,有1例出现腹胀,2例排气过多,对照组患者有4例出现恶心,有2例出现排气过多,有4例出现腹胀,对照组不良反应发生率高于观察组,差异有统计学意义(P<0.05)。结论:对2型糖尿病合并餐后低血糖患者应用阿卡波糖治疗能有效减少患者低血糖的发生,改善患者空腹血糖及餐后血糖水平,不良反应率较低。
作者 王捷
出处 《陕西医学杂志》 CAS 2013年第12期1609-1610,共2页 Shaanxi Medical Journal
  • 相关文献

参考文献7

  • 1罗俊,燕纯伯.颈动脉超声对动脉粥样硬化性疾病的研究进展[J].心血管病学进展,2005,26(1):1-4. 被引量:84
  • 2Geroulakos G,OcGorman DJ,Kalediki E,et al.The carotid intima-media thickness as a marker of the presence of severe symptomatic coronary artery disease.Eur Heart J,1994,15 (6):781-785.
  • 3Rosfors S,Hallerstam S,Jensen-urstad K,et al.Relationship between intima-media thickness in the common carotid artery and atherosclerosis in the carotid bifurcation[J] .Stroke,1998,29(7):1378-1382.
  • 4Sorensen KE,Kriteensen IB,Celermajer DS.Atherosclerosis in the human brachial artery[J] .J Am Coll Cardiol,1997,29(2):318-322.
  • 5Salonen JT,Salonen R.Ultrasound B-mode imaging in observational studies of atherosclerosis progression[J] .Circulation,1993,(suppl)87:56-65.
  • 6雍永宏,陆凤翔,许迪,陈忠,陈莉,周蕾.颈动脉内膜-中层厚度对早发冠状动脉硬化性心脏病的预测价值[J].南京医科大学学报(自然科学版),2003,23(6):598-600. 被引量:16
  • 7Crouse JK.predictive valua of carotid 2-dimensional ultra-sound[J] .Am J cardiol,2001,88 (Suppl):27E-30E.

二级参考文献42

  • 1周青,郭瑞强,郝力丹.高频超声评价冠状动脉狭窄与颈动脉内-中膜厚度及面积的关系[J].中国超声医学杂志,2003,19(11):828-830. 被引量:30
  • 2Geroulakos G, O' Gorman D, Kalodiki E, et al. The carotid intima-media thicknessas a marker of the presence of severe symptomatic coronary heart disease[J]. Eur Heart J, 1994,15:781-785.
  • 3Crouse JR, Craven TE, Hagaman AP, et al. Association of coronary disease with segment specific intima-media thickening of the extra-cranial carotid artery [J] . Circulation,1995, 92:1141 - 1147.
  • 4Bots ML, Hoes AW, Koudstal PJ, et al. Commom carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdram study[J]. Circulation, 1997, 96:1432 - 1437.
  • 5Johannes H,John W, Wikstrand H, et al. Atherosclerotic change in the carotid artery bulb as measured by B - mode ultrasound are associated with the extent of coronary atherosclerosis[J]. Stroke, 1997, 28: 1189- 1194.
  • 6Salonen JT, Salonen R. Ultrasound B-mode imaging in observational studies of atherosclerosis progression [ J ].Circulation, 1993, (suppl)87:56-65.
  • 7Kallikazaros I, Isioufls C. Carotid artery disease as a marker for the presence of severe coronary, artery, diaease in patients evaluated for chest pain[J] . Stroke, 1999, 30(5): 1002 - 1007.
  • 8Crouse JR. predictive valua of carotid 2-dimensional ultrasound [ J ]. Am J cardiol, 2001, 88 (Suppl) : 27E - 30E.
  • 9Lemne C,Jogestrand T,Faire DU.Carotid intima-media thickness and plaque in borderline hypertension[T].Stroke,1995,26(1):34-39.
  • 10European Carotid Plaque Study Group.Carotid artery plaque compasition relationship to clinical presentation and ultrasound B-mode imaging[J].Eur J Vasc Endovasc Surg,1995,10(1):23-30.

共引文献97

同被引文献35

引证文献6

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部