摘要
目的：研究急性缺血性肠炎（AIC）患者血浆纤维蛋白原（Fg）升高的意义。方法：检测38例AIC患者发病72 h以内Fg水平,与36例正常对照组（N组）比较,分析AIC患者Fg水平升高的意义。AIC根据病变范围分为多结肠组（PC组）及单结肠组（SC组）,根据内镜下病变程度分为溃疡组（U组）和非溃疡组（NU组）,分析AIC患者Fg水平升高与病变范围及病变程度的关系。发病7~10 d后,15例AIC组患者复查Fg水平,研究Fg水平在AIC病情演变中的意义。结果：纳入研究的38例AIC患者的Fg平均水平为（4.31±1.05）g/L,显著高于36例N组的Fg平均水平（2.94±0.55）g/L,差异具有统计学意义（P〈0.01）;22例PC组Fg平均水平为（4.78±0.20）g/L,显著高于16例SC组的（3.84±0.92）g/L,差异具有统计学意义（P〈0.05）;17例U组Fg平均水平为（4.74±1.17）g/L,显著高于21例NU组的（3.94±0.79）g/L,差异具有统计学意义（P〈0.05）。发病7~10 d后,15例AIC患者复查Fg水平为（3.41±0.35）g/L,显著低于发病72 h以内的（4.31±1.05）g/L,差异具有统计学意义（P〈0.01）。结论：通过检测Fg水平可以协助诊断AIC;预测其病变范围以及病变程度,Fg水平可能与AIC病情演变过程有关。
Objective： To explore the significance of elevated fibr inogen（Fg） levels in acute ischemic colitis（AIC）. Methods： The levels of Fg were measured in 38 AIC patients within 72 h after onset, and were compared with those in 36 normal（N） group. The AIC patients were divided into pluraltity colon（PC） group and single colon（SC） group according to the range of lesion, and were divided into ulcer（U） group and non-ulcer（NU） group on the basis of the degree of the endoscopic lesions, for the sake of analyzing the correlations between the Fg levels of AIC and the range and the severity of the lesions. And the levels of Fg were measured in the 15 patients after the onset of 7~10 days to explore the significance of Fg levels in lesion evoluation of AIC. Results： Total 38 cases of AIC patients picked out in the study, and the Fg average was（4.31 ± 1.05） g/L, which was significantly higher than that of 36 N group [（2.94 ± 0.55） g/L, P0.01]; 22 cases of PC group, the Fg average was（4.78 ± 0.20） g/L, which was signifi- cantly higher than the 16 cases of SC group [（3.84±0.92） g/L, P0.05]; In 17 cases of U group, the Fg average was（4.74 ± 1.17） g/L, which was significantly higher than the NU group [（3.94 ± 0.79） g/L, P0.05]. And 7~10 days after onset, the Fg average level of the 15 AIC was（3.41±0.35） g/L, which was significantly lower than the figure of the onsets within 72 h [（4.31 ± 1.05） g/L, P0.01]. Conclusion： The detection of Fg levels may assist in the diagnosis of AIC, and predict the range and the severity of the lesions. Fg levels may be associated with the evoluation of the AIC.
出处
《温州医学院学报》
CAS
2013年第11期749-751,共3页
Journal of Wenzhou Medical College
