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化积颗粒治疗小儿功能性腹痛215例临床观察 被引量:6

Clinical Observation on 215 Children with Functional Abdominal Pain treated with Huaji Granules
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摘要 目的:探讨化积颗粒治疗小儿功能性腹痛的临床疗效及安全性。方法:将430例功能性腹痛患儿随机分为对照组及观察组各215例,对照组给予消旋山莨菪碱、多潘立酮等西药治疗,观察组给予化积颗粒治疗,对比两组疗效、安全性。结果:观察组总有效率95.81%,优于对照组的71.63%,观察组中医症候评分(0.53±0.16)分较对照组(1.46±0.33)分降低更为明显,观察组不良反应发生率1.39%低于对照组的17.21%,差异均有统计学意义(P<0.05)。结论:化积颗粒治疗小儿功能性腹痛,健脾益胃、理气消积,多机制干预胃肠功能,可明显缓解临床症状,减少疾病复发,疗效确切,无明显不良反应,值得临床进一步研究推广。 Objective:to investigate efficacy and safety of Huaji granules for treating children with functional abdominal pain. Methods: 430 children with functional abdominal pain were randomly assigned control group and Observation Group, control group took western medicine such as racemic hyoscyamine and domperidone, Observation Group received Huaji granule, compared efficacy and safety of two groups. Results: Observation group' s total effective rate (95.81%), was higher than control group (71.63%), Observation group' s TCM symptom scores (0.53 ± 0.16) reduce more significantly than the control group (1.46 ± 0.33 ). Observation Group had AE inci-dence of 1.39% lower than that of control group ( 17.21% ) ( P 〈 0.05 ). Conclusion: Huaji Granules can treat children with function-al abdominal pain by invigorating the spleen and stomach, regulating Qi and promoting digestion. It can alleviate clinical symptoms, control disease recurrence, therefore is recommended to be used in clinic.
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出处 《世界中医药》 CAS 2013年第11期1295-1297,共3页 World Chinese Medicine
关键词 化积颗粒 消旋山莨菪碱 多潘立酮 小儿功能性腹痛 Huaji Granules Racemic hyoscyamine Domperidone Children with functional abdominal pain
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