摘要
目的 探讨微血管形成在非小细胞肺癌中的表达及其临床意义。方法 采用免疫组织化学的方法 ,对33例病人非小细胞肺癌进行分析。结果 全部 33例非小细胞肺癌中 ,淋巴结转移组 :微血管密度 (MVD)为 43 6± 2 2 3,非淋巴结转移组 :为 2 4 6± 17 3(P <0 .0 1)。生存期 >5年 ,MVD为 2 2 4± 16 8,生存期 <半年者为 5 8 6± 2 3 4,P <0 0 1。结论MVD对非小细胞肺癌的转移及预后有预测作用 ,它的检测可为临床诊治提供更多依据。
Objective: To research into the expression of microvessel density and its significance in nonsmall cell lung cancer. Methods: Thirty three patients were analysed through the immunohistochemistry method. Results: The expressions of MVD were 43 3±22 3 in the mestastatic lymph node group and 24 6±17 3 in the group with the no lymph node involving (P<0 01). The expressions of MVD in patients who lived more than 5 years and lived less than half a year were respectively 22 4±16 8 and 58 6±23 4 (P<0 01). Conclusion: MVD has predictive function for the prognosis and the metastasis of NSCLC and can form the basis for the clinical work.
出处
《泰山医学院学报》
CAS
2000年第4期319-320,共2页
Journal of Taishan Medical College
