摘要
目的探讨舌下含服粉尘螨滴剂特异性免疫对变应性鼻炎患者生存质量的影响。方法选取2010年2月至2012年3月期间我院收治的80例变应性鼻炎患者的临床资料进行回顾性分析,分成实验组和对照组,每组40例,对照组采用传统皮下注射特异性免疫治疗,实验组采用舌下含服粉尘螨滴剂治疗。结果实验组的有效率(86.7%)明显高于对照组(73.3%,P<0.05);实验组治疗后的临床评分(2.4±0.5)明显低于对照组(6.2±1.4,P<0.05);实验组的活动、睡眠以及情感等项目评分均低于对照组(P<0.05),实验组的生活质量评分(6.37±2.06)低于对照组(9.18±3.22,P<0.05)。结论舌下含服粉尘螨滴剂特异性免疫与传统皮下注射特异性免疫对变应性鼻炎患者具有同等、较好的临床疗效,并可明显提高患者的生活质量,为患者提供更加安全有效的治疗方案。
Objective To investigate the effect of dust mite sublingual drops on the quality of life in patients with allergic rhinitis. Methods The clinical data of 80 patients with allergic rhinitis in our hospital from February 2010 to March 2012 were analyzed retrospectively, and divided into experimental group and control group ,40 patients in each group. Control group was given traditional subcutaneous injection specificity immunization, experimental group was giv- en dust mites sublingual drops. Results The effective rate of experimental group （ 86.7% ） was significantly higher than that of control group （ 73.3% , P 〈 0. 05 ） ; the clinical score of experimental group after treatment （ 2. 4 ± 0. 5 ） was significantly lower than that of control group （ 6. 2 ± 1.4, P 〈 0. 05 ） ; the activities, sleep, and emotional scores of experimental group were lower than those of control group （ P 〈 O. 05 ） , quality of life score of the experimental group （6. 37 ± 2. 06 ） was lower than that of control group （9. 18 ±3.22, P 〈 0. 05 ）. Conclusion Sublingual dust mite drops specific immune system and subcutaneous injection specific immunity in allergic rhinitis patients have equal, good clini- cal efficacy, and they can significantly improve the quality of life of patients, provide more safe and effective programs for patients.
出处
《实用药物与临床》
CAS
2013年第11期1043-1045,共3页
Practical Pharmacy and Clinical Remedies
关键词
粉尘螨滴剂
变应性鼻炎
生存质量
Dust mite sublingual drops
Allergic rhinitis
Quality of life
