摘要
目的:收集民国以前文献中肺癌治疗的方药,探讨古代文献中肺癌治疗方药的规律,为临床诊治提供思路和方法。方法:将文献学方法与因子、聚类分析方法相结合,运用中医理论知识对民国以前文献中肺癌治疗的方药进行研究。结果:得到4个体现民国以前肺癌治疗特点的公因子,F1:川乌、干姜、黄连等;F2:陈皮、桔梗等;F3:生姜、甘草等;F4:葶苈子、大枣;得到4个聚类方,C1:陈皮、桔梗、人参等;C2:葶苈子、大枣等;C3:肉桂、吴茱萸;C4:木香、槟榔等。结论:肺癌是本虚标实,虚实夹杂之病,累及肺脾肾三脏,正气不足,痰湿,气滞,血瘀等邪气留踞是发病的主要病机特点;治疗时抓住病机特点,多应用补虚、理气、活血和化痰等法。
Objective： By investigating the regulation of prescription-herbs on treating lung cancer in ancient literatures, to provide the new thoughts for the clinical diagnosis and treatment. Methods： The prescription-herbs were summarized from the ancient literatures by using methods of literatures research combined with statistic analysis. Results： Four factors which reflected the treatment characteristics were extracted. FI： Radix aconiti, Dried ginger, Coptis chinensis, et al; F2： Tangerine peel, Balloonflower, et al; F3： Ginger, Glycyrrhiza, et al; F4： Lepidium seed, Jujube date; Four prescriptions were summarized, CI： Tangerine peel, Balloonflower, radix ginseng, et al; C2： Lepidium seed, Jujube date, et al; C3： Cinnamon and Evodia rutaecarpa; C4： Radix auckladiae and Areca catechu, et al. Conclusions： Lung cancer was a disease of fundamental deficiency and incidental excess, involving with lung, spleen and kidney. Deficiency of healthy qi, phlegm-dampness, qi stagnation, blood stasis and the others were the main characteristics of pathogenesis of lung cancer. Adopting different methods according to the characteristics of pathogenesis, including reinforcing the healthy qi, regulating qi, activating blood circulation, dispelling Phlegm and so on.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2013年第12期3750-3752,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
肺癌
文献研究
方药规律
因子分析
聚类分析
Lung cancer
Literatures study
Prescription-herb＇s rules
Factor analysis
Cluster analysis
