摘要
目的研究偏头痛患者药物过度使用性头痛(MOH)的有关因素及其临床特点。方法调查22例MOH、98例非MOH偏头痛患者的临床资料及头痛发作状况、用药史和药物戒断症状。采用视觉模拟评分法(VAS)和偏头痛致残程度评估量表(MIDAS)评定患者的头痛程度及其致残程度。结果 MOH组的年龄、病程及有偏头痛家族史的比率显著高于或长于非MOH组(均P<0.05);VAS评分及MIDAS评分均明显高于非MOH组(均P<0.001)。MOH组患者中过量服用非甾体抗炎药的最多(12例,54.5%),其他有吗啡、苯二氮艹卓类和中成药。结论 MOH的有关因素为年龄、病程及家族史,其头痛和致残程度明显重于无MOH患者。MOH患者过量服用的药物以非甾体抗炎药为多。
Objective To investigate the related factors and clinical features in migraine patients with medication-overuse headache（MOH）. Methods The clinical data and headache attack status, history of drug, drug withdrawal symptoms in 22 migraine patients with MOH and 98 migraine patients without MOH were investigated. Visual Analogue Scale （VAS） and Migraine Disability Assessment Scale （MIDAS） were assessed the degree of headache and degree of disability. Results Age, course of disease and family history of migraine in MOH group were significantly higher or longer than those in non MOH group （ all P 〈 0. 05 ）. VAS scores and MIDAS scores in MOH group were significantly higher than those in non MOH group（ all P 〈 0. 001 ）. Non-steroidal anti-inflammatory drugs （NSAID） accounted for the most in MOH group （12 cases, 54. 5%）, while other drugs included morphine, benzodiazepines and Chinese medicine. Conclusions The related factors of MOH are age, course of disease and family history. Headache severity and degree of disability were more severe in patients with MOH than without. The most drug of medication-overuse in patients with MOH is NSAID.
出处
《临床神经病学杂志》
CAS
北大核心
2013年第6期421-423,共3页
Journal of Clinical Neurology
关键词
偏头痛
药物过度使用性头痛
头痛程度
偏头痛致残程度
migraine
medication-overuse headache
headache severity
migraine disability assessment
