摘要
目的研究血清学指标联合检测在乳腺癌早期诊断中的价值。方法将乳腺癌患者纳入观察组、乳腺良性疾病患者纳入良性对照组、健康体检者纳入健康对照组,检测外周血中CEA、CA125、CA153和CA199的含量。结果观察组患者CEA、CA125、CA153、CA199水平明显高于良性对照组和健康对照组,并且与TNM分期呈正相关关系;四项指标联合检查的灵敏度为93.33%、特异度为91.25%,均高于四项指标单独检测。结论 CEA、CA125、CA153和CA199含量与肿瘤的TNM分期相关,联合检查能提高诊断的灵敏度和特异度,在乳腺癌的早期诊断中具有积极的临床价值。
Objective To study the value of combined detection of serological indexes in the early diagnosis of breast cancer. Methods The patients with breast cancer, patients with benign breast disease and health people conducted physical examination were selected as the observation group,the benign control group and the health control group respectively,and the levels of peripheral blood CEA,CA125,CA153 and CA199 were measured. Results The levels of CEA, CA125, CA153 and CA199 of patients in the observation group were significantly higher than those in the benign control group and the health control group,and were positively correlated with the TNM staging; The sensitivity and specificity of combined detection of four indexes were 93.33% and 91.25% respectively,and were higher than four indexes detection alone. Conclusion The levels of CEA,CA125,CA153 and CA199 are correlated with the TNM staging of tumor,and the combined detection of four indexes can increase the diagnostic sensitivity and specificity,and has active clinical value in the early diagnosis of breast cancer.
出处
《中国医药科学》
2013年第23期139-140,共2页
China Medicine And Pharmacy
关键词
乳腺癌
癌胚抗原
糖类抗原
TNM分期
Breast cancer
Carcinoembryonic antigen
Carbohydrate antigen
TNM staging
