摘要
目的 观察硝苯地平在妊娠高血压疾病患者中的应用效果与安全性.方法 选取2011年5月～2013年3月于本院进行治疗的72例妊娠高血压患者为研究对象,将其随机分为对照组36例和观察组36例,对照组仅给予硫酸镁治疗,观察组在对照组的基础上加用硝苯地平,然后将两组的血压控制总有效率、不良反应发生率与治疗前后的平均动脉压（MAP）、全血高切黏度（ηbH）、全血低切黏度（ηbL）及血浆黏度（ηp）进行对比.结果 观察组的血压控制总有效率高于对照组,MAP、ηnH、ηbL及ηp低于对照组（均P＜0.05）,而两组不良反应发生率差异无统计学意义（P＞0.05）.结论 硝苯地平在妊娠高血压患者中的治疗效果较好,安全性较高,对于血压与血黏度的调整也有较好作用.
Objective To observe the effect and safety of nifedipine in the patients with hypertensive disorder compli- cating pregnancy. Methods 72 patients with hypertensive..disorder complicating pregnancy in our hospital from May 2011 to March 2013 were selected as research objects, and they were randomly divided into control group （36 cases） and observation group （36 cases）,then the control group was only treated with magnesium sulfate,the observation group was treated with nifedipine on basis of control group,then the total blood pressure control effective rate,adverse reaction rate and MAP,ηbH,ηbL,ηp before and after the treatment of two groups were compared. Results The total blood pres- sure control effective rate of observation group was higher than that of control group, MAP,ηbH,ηbL and ηp were low- er than those of control group（P〈0.05）,while the adverse reaction rate of two groups had no obvious difference（P〉0.05）. Conclusion The effect of nifedipine in the patients with hypertensive disorder complicating pregnancy is better, and safety is definitely,it plays better role in improving the blood pressure and blood viscosity.
出处
《中国当代医药》
2013年第32期86-87,共2页
China Modern Medicine
关键词
硝苯地平
妊娠高血压
疗效
安全性
Nifedipine
Hypertensive disorder complicating pregnancy
Effect
Safety
