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贝那普利联合乐卡地平治疗轻中度高血压的近期疗效和安全性评价

Efficacy and safety of benazepril combining with lercanidipine treatment for mild to moderate hypertension
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摘要 目的观察贝那普利联合乐卡地平对轻、中度高血压的治疗效果和安全性。方法选取104例轻、中度高血压患者作为研究对象,随机分为两组。对照组单纯使用贝那普利治疗,实验组使用贝那普利联合乐卡地平治疗,观察比较两组疗效。结果实验组患者治疗8周时,其收缩压与舒张压与对照组比较,差异有统计学意义(P<0.05);两组患者不良反应比较,差异无统计学意义(P>0.05)。结论对轻、中度高血压患者给予贝那普利联合乐卡地平治疗有较好的效果,安全性高,值得应用。 Objective To observe the efficacy and safety ofBenazepril combitfing with lercanidipine treammnt for mild m moderate hypertension. Methods 104 cases of mild to moderate hypertensive patients as research subjects were randomly divided into two groups. Control group used benazepril, while the experinaental group used benazepfil combining with lercarfidipine. Then observed and compared therapeutic effects of the two groups. Results After treating for 8 weeks, systolic blood pressure and diastofic blood pressure of the experimental group were different fi'om the control group. And the differences were significant ( P 〈 0.05 ) .Adverse reactions in patients of two groups which had compare with each other were not sigalificanrly different ( P 〉 0.05 ) . Conclusion Patients with mild to moderate hypertension who had been given benazepril combining with lercamdipine treatment has a good clinical effecacy.The treaunent is safe, and worth wild applications.
作者 杨显峻
出处 《中国处方药》 2013年第6期30-31,共2页 Journal of China Prescription Drug
关键词 高血压 贝那普利 乐卡地平 Hypertension Mild to Moderate Benazepril Lercanidipine
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