期刊文献+

伊托必利与氟西汀联用方案治疗功能性消化不良疗效观察

下载PDF
导出
摘要 目的探讨伊托必利与氟西汀联用方案治疗功能性消化不良的临床疗效。方法选取2010年4月-2013年4月治疗的62例功能性消化不良患者为研究对象,随机分为实验组和对照组各31例,实验组给予伊托必利和氟西汀联合方案治疗,对照组单纯给予伊托必利进行治疗,对比观察两组患者的临床疗效。结果实验组患者31例,基本痊愈17例,好转12例,无效2例,有效率为93.5%。对照组患者31例,基本痊愈12例,好转13例,无效6例,有效率为80.6%。实验组患者治疗效果明显优于对照纽,P〈0.05,有显著性差异,具有统计学意义。结论伊托必利与氟西汀联用方案治疗功能性消化不良临床效果显著,是一种治疗功能性消化不良安全有效的方法。
作者 贾敏
出处 《航空航天医学杂志》 2013年第12期1547-1548,共2页 Journal of Aerospace medicine
  • 相关文献

参考文献4

二级参考文献50

  • 1[1]Dominguez-Munoz JE.Targeting the abnormalities of gastroduodenal functions in functional dyspepsia[J].Dig Dis,2001,19(3)∶195-200.
  • 2[2]Iwanaga Y,Miyashita N,Saito T,et al.Gastroprokinetic effect of a new benzamide derivative itopride and its action mechanisms in conscious dogs[J].Jpn J Pharmacol,1996,71(2)∶129-137.
  • 3[3]Iwanaga Y,Kimura T,Miyashita N,et al.Characterization of acetylcholinesterase-inhibition by itopride[J].Jpn J Pharmacol,1994,66(3)∶317-322.
  • 4[4]Harasawa S,Miwa T.Effect of itopride hydrochloride on gastric emptying in chronic gastritis patients[J].Jpn Pharmacol Ther,1993,11(21)∶4189-4195.
  • 5[5]Nakajima M,Uematsu T,Nakajima S.Phase I study of HSR-803[J].Jpn Pharmacol Ther,1993,11(21)∶4157-4173.
  • 6[6]Mushiroda T,Douya R,Takahara E,et al.The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride,a gastroprokinetic agent:comparison with cisapride and mosapride citrate[J].Drug Metab Dispos,2000,28(10)∶1231-1237.
  • 7[7]Miyoshi A,Omata S,Miwa T,et al.Clinical effect of HSR-803 on digestive symptoms:early phase Ⅱ study[J].Jpn Pharmacol Ther,1993,11(21)∶4175-4187.
  • 8[8]Miyoshi A,Masamune O,Sekiguchi T,et al.Clinical evaluation of itopride hydrochloride for gastrointestinal symptoms associated with chronic gastritis:multi-center double-blind clinical trial using cisapride as control drug[J].Jpn Pharmacol Ther,1994,12(4)∶261-279.
  • 9[9]Miyoshi A,Masamune O,Sekiguchi T,et al.Dose finding study of a gastroprokinetic agent,HSR-803,on gastrointestinal complations: late phase II study[J].Jpn Pharmacol Ther,1993,11(3)∶2107-2128.
  • 10[10]Hirakawa T,Yoshizawa M,Kagawa T,et al.Clinical effect of the peristalsis enhancer itopride hydrochloride on the digestive symptoms of chronic gastritis[J].Clinical Report,1993,15(27)∶5901-5906.

共引文献303

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部