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碳青霉烯类抗生素研究进展 被引量:23

Advances in carbapenems
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摘要 碳青霉烯类抗生素是一类抗菌活性强、抗菌谱广的非典型β-内酰胺类抗生素,对革兰阳性、阴性需氧菌和厌氧菌均有强大的抗菌作用。本文就碳青霉烯类药物的临床应用现状、存在的问题及研究方向等作一综述。 Carbapenems are a class of atypical [3-lactam antibiotics with high antibacterial activity and broad antibacterial spectrum, including Gram-positive and Gram-negative aerobic and anaerobic bacteria. This review focused on the clinical application status, existing problems and research direction of carbapenems.
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2013年第12期927-931,共5页 Chinese Journal of New Drugs and Clinical Remedies
基金 科技部十二五"重大新药创制"科技重大专项基金(2011ZX09302-003-01)
关键词 碳青霉烯类 碳青霉烯酶 β-内酰胺抗药性 药物不良反应 carbapenems carbapenemases beta-lactam resistance adverse drug reactions
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