摘要
安全性评价是转基因农作物商品化应用的必要环节。组学技术能在转录物、蛋白质、代谢物水平上对转基因农作物进行无偏倚的安全性评价。文章综述了近10年来应用转录组学、蛋白质组学和代谢物组学技术评价转基因农作物非预期效应的研究进展,结果表明在转基因农作物非预期变异中,环境因素(种植地点和季节)和基因型差异比转基因本身的影响更大。
Safety assessment is the essential process for commercial application of genetically modified （GM） crops. Omics techniques can be used to evaluate the safety of GM crops unbiasedly at different biological levels, such as tran- scripts, proteins and metabolites. In the present review, the researches on unintended effects assessment of GM crops using transcriptomic, proteomic and metablomic techniques in recent ten years have been summarized. The facts show that the environmental factors （growing area and season） and genotype difference play greater roles than gene insertion does for most unintended variations in GM crops.
出处
《遗传》
CAS
CSCD
北大核心
2013年第12期1360-1367,共8页
Hereditas（Beijing)
基金
国家自然科学基金项目(编号:30871511)
农业部转基因新品种培育重大专项项目(编号:2011ZX08010-003)资助
