摘要
目的探讨重症患者血清肌酸激酶(CK)与动脉血乳酸的相关性。方法检测112例重症患者的CK及动脉血乳酸,进行急性生理和慢性健康状况(APACHE)Ⅱ评分;将患者分为CK正常组及高CK组。结果高CK组的血乳酸、APACHEⅡ评分均显著高于CK正常组,差异有统计学意义(P<0.05),高CK组CK与血乳酸及APACHEⅡ评分呈正相关(r=0.316,0.415;P=0.021,0.002),CK正常组无明显相关性。结论高CK水平对判断重症患者病情严重程度有一定的临床价值。
Objective To investigate the correlation of creatine kinase （CK） with lactic acid in critically ill patients. Methods A total of 112 critically ill patients in ICU were enrolled fl＇om January 2012 to January 2013. CK and arterial blood lactate were detected. Acute physiology and chronic health evaluation （APACHE） II score were assessed. Patients were divided into normal CK group and high CK group. Results Lactate level and APACHE II score of the high CK group were significantly higher than those of the normal CK group （P 〈 0.05 ）. In high CK group, the level of CK was positively correlated with APACHE II score （ r = 0. 415,P = 0. 002） and the lactate level （ r =0. 316 ,P =0.021 ）. No significant correlation was found between CK with blood lactate and APACHE II score in normal CK group. Conclusion The high serum CK levels is positively correlated with the severity in critically ill patients.
出处
《安徽医学》
2013年第12期1788-1789,共2页
Anhui Medical Journal
