盐酸氨基葡萄糖治疗神经根型颈椎病的临床疗效观察被引量：1

下载PDF

导出

摘要目的:观察盐酸氨基葡萄糖对神经根型颈椎病临床疗效和不良反应。方法:将129例神经根型颈椎病患者随机分成对照组和治疗组,对照组:颈椎操锻炼、颈枕带牵引,1次/d;治疗组:颈椎操锻炼、颈枕带牵引,同时口服盐酸氨基葡萄糖片1片/次,2次/d,6周后进行疗效与安全性评价。结果:治疗组6周后总有效率与对照组比较差异有统计学意义(P<0.05)。结论:盐酸氨基葡萄糖治疗神经根型颈椎病可以较为明显地提高临床疗效,在物理治疗基础上可以推荐使用。

作者陈刚

机构地区江苏省南京市秦淮区蓝旗社区卫生服务中心

出处《吉林医学》 CAS 2013年第35期7407-7408,共2页 Jilin Medical Journal

关键词神经根型颈椎病盐酸氨基葡萄糖临床疗效不良反应

分类号 R681.55 [医药卫生—骨科学]

引文网络
相关文献

参考文献4

1邱贵兴.骨关节炎诊治指南(2007年版)[J].中华关节外科杂志（电子版）,2007,1(4):254-256. 被引量：403
2王蕾,王健,王惠珍.氨基葡萄糖与美洛昔康治疗老年膝骨关节炎疗效的对比观察[J].中国老年学杂志,2010,30(18):2691-2692. 被引量：9
3张伟滨,庄澄宇,李建民,杨志平,陈晓亮.盐酸氨基葡萄糖治疗骨性关节炎有效性与安全性评价[J].中华外科杂志,2007,45(14):998-1001. 被引量：52
4骨关节炎诊断及治疗指南[J].中华风湿病学杂志,2010,14(6):416-419. 被引量：1380

二级参考文献16

1邱贵兴,翁习生,张克,周乙雄,娄思权,王以朋,李为,张洪,刘岩.盐酸/硫酸氨基葡萄糖治疗骨关节炎的平行对照临床研究[J].中华医学杂志,2005,85(43):3067-3070. 被引量：93
2Simon LS.Role and regulation of cyclooxygenase-2 during inflammation[J].Am J Med,1999;106(5):375-425.
3Adams ME.An analysis of clinical studies of the use of crosslinked hyaluronan hylain in the treatment of osteoarthritis[J].J Rheumatol Suppl,1993;39:16-8.
4Ceoff Mc Col.Glucosamine for osteoarthritis of the knee[J].Aust Prescr,2004;27(1):61-3.
5Nakamura H,Shibakawa A,Tanaka M,et al.Effects of glucosamine hydrochloride on the production of prostaglandin E2,nitrict oxide and metalloproteases by chondrocytes and synoviocytes in osteoarthritis[J].Clin Exp Rheumatol,2004;22(3):293-9.
6Largo R,Alvarez-Soria MA,Diez-Ortego I,et al.Glucosamine inhibits IL-1beta-induced NFkappaB activation in human osteoarthritic chondrocytes[J].Osteoarthritis Cartilage,2003;11(4):290-8.
7Ted a Y,Tsukimura N. A six-month followup of a randomized trial comparing the efficacy of a lateral-wedge insole with subtalar strapping and an in-shoe lateral-wedge insole in patients with varus deformity osteoarthritis of the knee. Arthritis Rheum, 2004,50: 3129-3136.
8Sanekez C, Mateus MM, Defresne MP, et al. Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin lbeta and nonsteroidal anti-inflammatory drugs. J Rheumato1,2002,29:772-782.
9McAlindon TE, Lavalley MP, Gulin IP, et al. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA ,2000,283 : 1469-1475.
10da Camara CC, Dowless GV. Glucosamine sulfate for osteoarthritis. Ann-phammcother, 1998,32 : 580 -587.