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结肠肝样腺癌1例并文献复习 被引量:3

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摘要 目的探讨结直肠肝样腺癌的临床病理特征。方法回顾1例横结肠肝样腺癌的临床资料,行病理组织学和免疫组化观察并复习相关文献。结果本例及17例文献报道(共18例)结直肠肝样腺癌中男性多见,年龄37~75岁,中位年龄53岁。血清AFP常明显升高。镜下肝样腺癌常由分化好的管状、乳头状腺癌和肝样分化区组成。肝样分化区瘤细胞呈小梁状或实片状排列,瘤细胞大,多边形,胞质丰富。肿瘤间质血管丰富,常见大量脉管瘤栓。肝样腺癌常表达AFP、CEA、CK19,部分表达Hepatocyte。容易出现肝转移,多在1年内死亡。结论结肠肝样腺癌少见,有较强的侵袭和转移能力,预后差,临床上应注意与转移性肝细胞癌鉴别。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2013年第12期1366-1368,共3页 Chinese Journal of Clinical and Experimental Pathology
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