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诱导化疗联合同期放化疗与同期放化疗治疗局部晚期鼻咽癌的对比研究 被引量：8

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摘要 目的:探讨与对比诱导化疗联合同期放化疗与同期放化疗治疗局部晚期鼻咽癌(LA-NPC)的临床效果。方法:选择局部晚期鼻咽癌患者110例,根据患者实施诱导化疗的意愿分成研究组与对照组,每组55例,研究组采用诱导化疗联合同期放化疗进行治疗,对照组给予同期放化疗进行治疗。生存分析通过KAPLAN-MEIER方法进行,观察两组的临床治疗结果。结果:在OS(总生存率)、FFS(无瘤生存率)、LR-FFS(无局部区域复发生存率)以及D-FFS(无远处转移生存率)上,两组差异无统计学意义(P>0.05);在Ⅱ期鼻咽癌FFS(无失败生存)上,研究组要优于对照组(P<0.05)。结论:诱导化疗联合同期放化疗和同期放化疗相比,尽管没有提升患者的FFS、OS、D-FFS和LR-FFS,然而却对Ⅱ期鼻咽癌的无失败生存(FFS)进行了改善。和同期放化疗相比,诱导化疗联合同期放化疗更能使患者的生存率得到提高。
作者 苏琼菲 彭苗 刘晓清 杨帆 丁颖
机构地区 广东药学院附属第一医院肿瘤科
出处 《吉林医学》 CAS 2013年第36期7633-7633,共1页 Jilin Medical Journal
关键词 诱导化疗 同期放化疗 局部晚期鼻咽癌 治疗结果
分类号 R739.63 [医药卫生—肿瘤]
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共引文献33

同被引文献64

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吉林医学
2013年 第36期

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