摘要
目的评价Lipoclear脂质清除剂消除脂血对常规生化项目检测的干扰。方法分别收集正常标本40例为对照组,脂血标本35例为实验组,经Lipoclear试剂处理,同时测定处理前、后18项生化指标,记录检验结果,计算相关系数及相对偏差,以美国临床医学检验部门修正法规(CLIA′88)允许总误差(TEa)的1/2为标准,判断其偏差是否为临床可接受。结果对照组的18项生化指标除无机磷(P)、总蛋白(TP)、三酰甘油(TG)的相对偏差高于1/2 TEa外,其余指标均低于1/2 TEa;实验组标本经该试剂处理后其生化结果明显得到改善。结论 Lipoclear脂质清除剂消除脂血的干扰效果较好,且操作简单、快速,对多数临床常规生化项目无明显干扰现象,值得在临床中推广应用。
Objective To evaluate the effect of eliminating lipemia interference for conventional biochemical tests by lipoclear. Methods 40 cases of normal samples were chosen as the control group and 35 cases of lipid blood samples as the experimental group. 18 biochemical parameters were detected before and after the lipoclear reagent treatment. The test results were recorded, and the correlation coefficient and the relative deviation was calculated. 1/2 of the U.S. clinical correction inspection department regulations （CLIA ＇88） allowed total error （TEa） as the standard, We determined whether the deviation is clinically acceptable. Re- sults 18 biochemical indicators in the control group except for inorganic phosphorus （P）, total protein （TP） and triglyceride （TG） relative deviation were 〉 1/2 TEa, and the other indicators were 〈 1/2 TEa. The biochemical outcomes of experimental group was significantly improved after reagent treatment. Conclusion The effect of eliminating the lipemia interference by lipoclear is good, and the operation is simple, fast and without significant interference for most routine clinical biochemistry projects, and it is worthy of clinical application.
出处
《国际检验医学杂志》
CAS
2014年第1期72-74,共3页
International Journal of Laboratory Medicine
关键词
脂血
实验室技术和方法
三酰甘油类
lipemia
interference
biochemical indicators
lipoclear
acceptability assessment
