摘要
目的了解剖宫产术后手术切口感染的病原菌分布,并对其耐药性进行分析,为预防和控制手术切口感染提供依据。方法选取妇产科2008年1月-2013年8月行剖宫产手术后并发切口感染的86名产妇为研究对象,采集切口分泌物进行细菌培养和鉴定,纸片扩散法进行药敏试验。结果 86份切口分泌物中共培养出121株病原菌,以大肠埃希菌、肠球菌属、铜绿假单胞菌为主,分别占38.8%、17.4%、11.6%;其中革兰阴性菌对氨苄西林、头孢类抗菌药物耐药性较高,而革兰阳性菌对青霉素、红霉素、氨苄西林等抗菌药物耐药性较高。结论剖宫产术后手术切口感染的病原菌复杂多样,且病原菌的耐药性不断增强,应合理使用抗菌药物,遏制耐药菌的增长。
OBJECTIVE To understand the distribution of pathogens causing surgical incision infections after cesarean section and analyze the drug resistance so as to provide guidance for prevention and control of surgical incision infections. METHODS Totally 86 puerperae complicated with postoperative incision infections, who underwent the cesarean section in department of gynecology and obstetrics from Jan 2008 to Aug 2013, were enrolled in the study, then the incision secretions were sampled for bacterial culture and identification, and the drug susceptibility testing was performed with the use of disc diffusion method. RESULTS A total of 121 strains of pathogens have been isolated from 86 incision secretions samples, among which the Escherichia coli, Enterococci, and Pseudomonas aeruginosa were dominant, accounting for 38. 8%, 17.4%, and 11.6%, respectively. The gram-negative bacteria were highly resistant to ampicillin and cephalosporins; while the gram-positive bacteria were highly resistant to penicillin, erythromycin, and ampicillin. CONCLUSION There are a variety of species of pathogens causing the surgical incision infections after the cesarean section, and the drug resistance of the pathogens is increasingly serious; it is necessary to reasonably use antibiotics so as to curb the increase of drug resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第2期464-465,468,共3页
Chinese Journal of Nosocomiology
基金
浙江省科研基金项目(2012-RG/RH-0010)
缙云县科技局基金项目(201342)
关键词
剖宫产切口
感染
病原菌
耐药性
Incision of cesarean section
Infection
Pathogen
Analysis of drug resistance
