摘要
目的探讨丙酸氟替卡松治疗过敏性鼻炎疗效及对患者免疫力的影响。方法选取该院2010年1月—2012年12月收治的80例过敏性鼻炎患者进行研究分析。80例患者按照数字随机法分为观察组和对照组,每组40例。观察组采用丙酸氟替卡松治疗,对照组采用酮替芬进行治疗,观察两组患者治疗的效果及治疗前后血清中血清免疫球蛋白(Ig)定量和IL-4及IL-12的含量变化。结果经研究发现,观察组有效率95.0%,与对照组80.0%相比,差异具有统计学意义,P<0.05。且治疗后,IL-4、IL-12的含量明显高于治疗前和对照组,差异均具有统计学意义,P<0.05。结论丙酸氟替卡松在治疗过敏性鼻炎有较好的疗效,且患者免疫力大大提高,值得临床推荐。
Objective To investigate the effect of allergic rhinitis treated with fluticasone propionate and its effect on the immune system of the patient. Methods 80 patients in Xiaotao First Hospital from January 2010 to December 2012 with allergic rhinitis were studied. 80 patients were randomly divided into two groups, the observation group and the control group. Each group had 40 patients. The observa- tion group was treated with fluticasone propionate, and the control group with ketotifen. The effects of treatment were observed. And ser- um IL-4 and IL-12 content change were also observed before and after treatment. Results The study found that the effective rate in the observation group was 95.0%, compared with 80.0% in the control group. The difference was statistically significant, P 〈 0.05. And after treatment, IL-4, IL-12 were significantly higher than before treatment and that in the control group. The differences were statistically sig- nificant,P 〈 0.05. Conclusions The fluticasone propionate in the treatment of allergic rhinitis has a good effect,and the patients greatly improved their immunity,which is worthy of recommendation.
出处
《安徽医药》
CAS
2013年第12期2142-2143,共2页
Anhui Medical and Pharmaceutical Journal
关键词
过敏性鼻炎
丙酸氟替卡松
免疫力
allergic rhinitis
fluticasone propionate
immunity
