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静脉注射替罗非班治疗不稳定型心绞痛疗效观察 被引量：4

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摘要 目的观察盐酸替罗非班治疗不稳定型心绞痛的安全性和疗效。方法将213例不稳定型心绞痛患者随机分为治疗组(104例)和对照组(109例)。对照组给予阿司匹林、低分子肝素、氯吡格雷等常规治疗;观察组在常规治疗上联用替罗非班以0.1μg/(kg·min)由微量泵持续泵入72h。比较两组治疗效果。结果治疗组72h的不良心血管事件(MACE)发生率明显低于对照组(2.9%比11.9%,P<0.05),对不稳定型心绞痛患者的症状和心电图的改善,治疗组高于对照组(94.2%比74.3%,68.3%比31.2%,P<0.05)。两组的主要不良反应为出血,但发生率差异无统计学意义(P>0.05)。结论静脉注射替罗非班治疗不稳定型心绞痛安全、有效,可进一步减少MACE的发生风险。
作者 李小芳 郭东华 白敏聪
机构地区 大同煤矿集团公司总医院
出处 《中西医结合心脑血管病杂志》 2013年第12期1437-1438,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词 不稳定型心绞痛 盐酸替罗非班 不良心血管事件
分类号 R541.4 [医药卫生—心血管疾病] R256.2 [医药卫生—中医内科学]
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参考文献7

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二级参考文献7

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共引文献12

同被引文献24

二级引证文献4

中西医结合心脑血管病杂志
2013年 第12期

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