摘要
目的分析医院专项整治后住院患者抗菌药物使用强度的作用效果,以提高医院抗菌药物合理使用水平。方法采用回顾性调查方法,按整治前(2010年1-8月)、整治后(2011年1-8月)进行分组,对两组抗菌药物使用强度(AUD)、各临床科室用药频度(DDDs)等数据进行统计分析。结果抗菌药物专项整治前的AUD为87.19,整治后为51.53,较整治前下降40.90%(P<0.05);临床科室专项整治前DDDs为346 409.80,整治后为168 733.10,较整治前下降51.29%(P<0.01),重点管理的抗菌药物包括喹诺酮类、氨基糖苷类、碳青霉烯类、林可霉素类、第三、四代头孢菌素等AUD均显著下降,下降率分别为49.78%、83.33%、50.00%、50.70%、60.02%、67.28%,但全院住院抗菌药物使用强度仍然>40DDD。结论抗菌药物专项整治可显著降低抗菌药物使用强度,促进抗菌药物的合理使用,对不合理用药仍需加强管理。
OBJECTIVE To evaluate the effect of special rectification on the use intensity of antibiotics for the hospitalized patients so as to improve the rationality of use of antibiotics.METHODS By means of retrospective survey, the subjects were grouped（from Jan to Aug,2010 as before the rectification;from Jan to Aug,2011 as after the rectification）,then the antibiotics use intensity（AUD）and medication frequency（DDDs）were statistically analyzed.RESULTS The AUD was 87.19 before the special rectification,51.53after the special rectification,with a decrease of 40.90%（P0.05）;the DDDs was 346409.80 before the special rectification,168733.10 after the special rectification,with a decrease of 51.29%（P0.01）.The antibiotics involving the special rectification included quinolones,aminoglycosides,carbapenems,lincomycins,and the third and fourth generation cephalosporins,with the AUD significantly decreased,which decreased by 49.78%,83.33%,50.00%,50.70%,60.02%, and 67.28%,respectively,but the use intensity of antibiotics of the whole hospital remained more than 40DDD. CONCLUSIONThe special rectification of antibiotics may contribute to the marked decrease of the use intensity of antibiotics and facilitate the reasonable use of antibiotics.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2014年第1期99-101,共3页
Chinese Journal of Nosocomiology
基金
贵港市科技攻关基金项目(1305044)
关键词
抗菌药物
用药频度
使用强度
专项整治
Antibiotic
Medication frequency
Use intensity
Special rectification
