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纳洛酮联合醒脑静注射液治疗双硫仑样反应的临床疗效分析 被引量:2

Clinical Efficacy of Naloxone Combined with Xingnaojing Injection in the Treatment of Disulfiram-like Reaction
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摘要 目的分析纳洛酮联合醒脑静注射液治疗双硫仑样反应的临床疗效。方法选取2008年1月—2013年1月在我院就诊的双硫仑样反应患者341例,将其随机分为治疗组172例和对照组169例。对照组给予常规基础治疗,治疗组在对照组治疗基础上给予纳洛酮联合醒脑静注射液治疗。结果治疗组心绞痛样发作比例、症状缓解时间、总治疗时间及再住院率均低于对照组(P<0.05)。结论纳洛酮联合醒脑静注射液治疗双硫仑样反应疗效显著,可显著降低心绞痛样发作比例、症状缓解时间、总治疗时间及再住院率。 Objective To analyze the clinical efficiency of Naloxone combine with Xingnaojing injection in the treat- ment of disulfiram - like reaction. Methods 341 patients with disulfiram - like reaction in our hospital were chosen from January 2008 to January 2013, they were randomly divided into treatment group (n = 172) and control group (n = 169). The control group was given the conventional therapy, on the basement of conventional therapy, the treatment group was given Naloxone com- bined with Xingnaojing injection. Results The proportion of angina - like episodes, relief time, total treatment time and read- mission rates in treatment group were lower than those of control group ( P 〈 0. 05 ). Conclusion Naloxone combined with Xing- naojing injection has a significant effect for the treatment of disullqram - like reaction, which can significantly reduce the propor- tion of angina - like episodes, relief, total treatment time and readmission rates.
作者 朱靖 于长久
出处 《实用心脑肺血管病杂志》 2014年第1期56-57,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 纳洛酮 醒脑静注射液 双硫仑样反应 治疗结果 Naloxone Xingnaojing injection Disulfiram - like reaction Treatment outcome
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