摘要
目的观察急性脑梗死早期使用氯吡格雷联合阿司匹林用药方法、疗效。方法 103例急性脑梗死患者随机分为三组,对照组予阿司匹林口服治疗,治疗组1予氯吡格雷联合阿司匹林口服治疗,治疗组2一经确诊即予氯吡格雷联合阿司匹林嚼服治疗,三组疗程均为14 d。观察三组治疗前后NIHSS总评分比较及疗效总有效率比较。结果治疗后NIHSS评分均有不同程度的改善,治疗组1治疗效果显著优于对照组,治疗组2治疗效果显著优于治疗组1(P<0.05);临床总有效率各组差异亦有统计学意义(P<0.05)。结论氯吡格雷联合阿司匹林治疗急性脑梗死疗效优于单用阿司匹林,而确诊后立即嚼服作用优于常规口服,急性脑梗死早期尽早发挥双抗治疗的作用会使患者获得更大的受益。
Objective Medication methods and efficacy of early use of Clopidogrel Hydrogen Sulfate Tablets in combination with aspirin in acute cerebral infarction. Methods 113 patients with acute cerebral infarction were randomly divided into three groups, the control group were given aspirin oral treatment, the first treatment group were given oral ctopidogrel in combination with aspirin therapy, the second treatment group once confirmed chew clopidogrel in combination with aspirin immediately. The course of treatment was 14 days. Observed total NIHSS score comparison and efficacy of 3 groups before and after treatment the total effective rate： Results After treatment NIHSS score improved in varying degrees, a therapeutic effect of the first treatment group was significantly better than the control group, the second treatment was significantly better than the first treatment group （P〈0.05）; clinical total efficiency of the group differences also was statistically significant （P〈0.05）.Conclusion Clopidogrel in combination with aspirin treatment of acute cerebral infarction more effective than aspirin alone, immediately after diagnosis chew superior to conventional oral. acute cerebral infarction as early as possible to play a double-antibody treatment patients will get greater benefit. If the early use of clopidogrel in Combination with aspirin in acute cerebral infarction, then the treatment would be better.
出处
《当代医学》
2014年第2期151-152,共2页
Contemporary Medicine
关键词
脑梗死
治疗
氯吡格雷联合阿司匹林
Cerebral infarction
Treatment
pClopidogrel in combination with aspirin
