期刊文献+

静脉注射丙种球蛋白治疗急性特发性血小板减少性紫癜的疗效观察 被引量:8

下载PDF
导出
摘要 目的探讨静脉注射丙种球蛋白治疗急性特发性血小板减少性紫癜(acute idiopathic thrombocytopenic purpura,AITP)的临床疗效。方法 60例ITP患儿按随机数字表法分为两组,对照组(n=30)给予常规激素治疗,观察组(n=30)在此治疗基础上采用静脉注射丙种球蛋白治疗。应用丙种球蛋白5 d,观察血小板回升及出血情况。结果观察组经静脉注射丙种球蛋白治疗后,病情迅速得到控制,总有效率为93.33%(28/30),对照组总有效率为66.67%(20/30),两组比较差异有统计学意义(P<0.05)。结论静脉注射丙种球蛋白治疗AITP疗效确切,值得临床应用。
作者 刚敏
出处 《中国医药指南》 2014年第3期60-61,共2页 Guide of China Medicine
  • 相关文献

参考文献4

二级参考文献35

  • 1George JN,Woolf SH, Raskob GE, et al. Idiopathic thrombocytopenie purpura: a practice guideline developed by explicit methods for the American Society of Hematology. Blood, 1996, 88(1) :3-40.
  • 2Mazzucconi MG, Fazi P,Bcrnasconi S,et al. Therapy with high- dose dcxamcthasonc (HD-DXM) in previously untreated patients affecled by idiopathic thrombocytopcnic purpura:a GIMEMA experience. Blood,2007,109 (4) : 1401-1407.
  • 3Ancona KG, Parker RI, Atlas iMP, et al. Randomized trial of high-dose methylprednisolone versus intravenous immunoglobulin for the treatment of acute idiopathic thrombocytopenic purpura in children. J Pediatr Hematol Oncol, 2002,24 ( 7 ) : 540- 544.
  • 4BCSH. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy. Br J Haematol,2003,120 ( 4 ) :574-596.
  • 5Jin F, Balthasar JP. Mechanisms of intravenous immunoglobulin action in immune thrombocytopenic purpura. Hum Immunol, 2005,66 (4) :403-410.
  • 6Park-Min Kit, Serbina NV, Yang W, et al. FcgammaRIII-dependent inhibition of interferon-gamma responses mediates suppressive effects of intravenous immune globulin. Immunity, 2007,26( 1 ) :67-78.
  • 7Lusher JM, Warrier I. Use of intravenous gamma globulin in children and adolescents with idiopathic thromboeytopenie purpura and other immune thromboeytopenias. Am J Med,1987,83 (4A) : 10-16.
  • 8Pcterlana D, Puccctti A, Simconi S, et al. Efficacy of intravenous immunoglobulin in chronic idiopathic pericarditis:report of four cases. Clin Rheumatol,2005,24( 1 ) :18-21.
  • 9Aledort LM, Salama A, Kovaleva L,et al. Efficacy and safety of intravenous anti-D immunogiobulin (Rhophylae) in chronic immune thromboeytopenie purpura. Hematology, 2007,12 (4) : 289-295.
  • 10i Ramadan KM, EI-Agnaf M. Efficacy and response to intravenous anti-D immunoglobulin in chronic idiopathic thrombocyto- pcnic purpura. Clin Lab Haematol,2005,27 (4) :267-269.

共引文献8

同被引文献60

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部