摘要
目的探讨南方寒、湿冬季长期脾胃虚寒老年女性胸痹后部分生理指标的变化及原因,为临床诊疗提供新思路。方法选择164例老年女性门诊患者及健康查体者为被试者,将被试者分为健康组(60例,正常组)、脾胃虚寒组(60例,虚寒组)以及在寒、湿冬季继发胸痹患者组(44例,继发组),检测缺血修饰白蛋白(IMA)、一氧化氮(Nitric Oxide,NO)及内皮素(Endothelin,ET)、血压(blood pressure,BP)、凝血酶原时间(prothrombin,PT)、部份活化凝血酶原时间(activated partial thromboplastin time,APTT)、纤维蛋白原(fibrinogen,FIB)、D-二聚体(D-dimer,DD)指标,比较其变化。结果虚寒组与正常组相比:FIB、DD、NO、ET升高,BP降低,差异有统计学意义(P<0.05);虚寒组与继发组相比:FIB、DD、NO、ET、IMA升高,BP降低,差异有统计学意义(P<0.05)。结论老年女性长期脾胃虚寒患者的心血管指标已处于异常状态,冬季继发胸痹可能与持续寒、湿刺激引起血液凝固性增加、NO、ET增加、血压降低有关。
Objective To explore the changes of some physiological indexes of elderly women with deficiency cold of spleen stomach for a long time after secondary thoracic obstruction at the cold-wet winter in southern China, and to analyze the cause and supply new thinking to clinical diagnosis. Methods 164 old-woman who came from outpatients and healthy individuals were chosen to study their some physiological indexes, they were divided into 3 groups, health group （60 cases, N group） , deficiency cold of spleen stomach for a long time group （60 cases, deficiency cold group） and secondary thorac- ic obstruction group under continuous low temperature and wet environment （44 cases, secondary group ）. Those indexes included IMA, nourishment（ NO ）, endothelin （ ET ）, blood pressure （ BP ）, prothrombin （ PY ）, activated partial thrombo- plastin time（ AFq＇F）, fibrinogen （FIB）, and D-dimer（DD）. Those indexes of three groups were compared. Results BP dropped, FIB, DD and NO increased were significantly compared deficiency cold of spleen stomach with those of normal group （ P 〈 O. O1 or 0.05 ）, after secondary thoracic obstruction, BP decreased, AF1T, FIB, DD, NO, ET and IMA signifi- cantly increased compared with those of deficiency cold group（ P 〈 0.01 or 0.05 ）. Conclusion Deficient cold of spleen stomach ; Thoracic obstruction ; Cold-wet ; Physiological indexes
出处
《中华全科医学》
2014年第1期124-126,共3页
Chinese Journal of General Practice
关键词
脾胃虚寒
胸痹
寒湿
生理指标
Deficient cold of spleen stomach
Thoracic obstruction
Cold-wet
Physiological indexes
