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面部脂溢性皮炎患者氧化应激水平及与其严重程度的关系 被引量:4

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摘要 目的探讨面部脂溢性皮炎(SD)患者氧化应激水平及与其严重程度的关系。方法以SD患者为研究对象(观察组),以年龄、性别与其匹配的健康体检者为对照组。首先比较两组血清过氧化氢酶(CAT)、超氧化物歧化酶(SOD)和丙二醛(MDA)水平的差异;然后,将SD患者根据临床评分分为轻度、中度、重度3组,比较各组CAT、SOD和MDA水平的差异;最后,进行SD严重程度临床评分与CAT、SOD和MDA的相关性分析。结果(1)观察组CAT、SOD显著低于对照组,MDA显著高于对照组,差异均有统计学意义(P<0.01)。(2)轻度、中度、重度3组CAT、SOD和MDA水平比较,差异均无统计学意义(P>0.05);3组间CAT、SOD和MDA水平两两比较,差异也无统计学意义(P>0.05)。(3)CAT、SOD和MDA与严重程度评分无明显相关性(P>0.05)。结论 SD患者处于氧化应激状态,但未发现与其严重程度相关。
出处 《广东医学》 CAS CSCD 北大核心 2013年第23期3620-3621,共2页 Guangdong Medical Journal
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参考文献8

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