摘要
目的探讨分析老年人与中青年人肺血栓栓塞症(PTE)患者的危险分层与治疗策略及预后。方法结合研究对象的危险分层、治疗策略及预后对两组患者进行研究。将两组患者分别分为高危、中危及低危,高危患者给予溶栓治疗,低危组给予抗凝治疗,中危患者抗凝及溶栓均有采用。疗效判断为治愈、好转、无效或恶化。结果 (1)老年组高危患者较青中年组多,差异有统计学意义(P<0.05);(2)青中年组给予溶栓治疗者较老年组多,差异有统计学意义(P<0.05)。青中年组患者疗效较好,痊愈患者较老年组多,无效及恶化者较老年组少,差异有统计学意义(P<0.05)。(3)两组治疗期间主要的不良反应为出血及INR延长,不良反应发生率较低。结论老年PTE高危患者较青中年人多,治疗难度更大,预后较差,因此,对不同年龄段的PTE患者应该首先做出准确的危险分层,并强调治疗的个体化原则。
Objective To analyze the correlation between risk stratification of patients of elderly and young patients with pulmonary thromboembolism and prognosis. Methods Combined with the risk stratification, the treat- ment strategy and prognostic study of the two groups of patients were analyzed. Then they were divided into the high risk, middle risk and low risk groups. The high risk group was given thrombolytic treatment, the low risk group was treated with anticoagulant therapy, and the medium risk group was given anti-coagulation and thrombolysis treatment. Results （ 1 ） The elderly patients in the high-risk group were more than young patients （ P 〈 0. 05 ）. （2） Young pa- tients received thrombolytic therapy more than elderly patients did （ P 〈 0. 05 ）. （3） The main adverse reactions in- cluded bleeding and prolonged INR. The incidence of adverse reactions was low. Conclusion Elderly patients in the high-risk PTE group are more than young and middle-aged patients, with difficult treatment and poor prognosis. Therefore, the different age of PTE patients should make accurate risk stratification, and emphasis on the individual treatment principles.
出处
《临床肺科杂志》
2014年第2期243-246,共4页
Journal of Clinical Pulmonary Medicine
关键词
肺血栓栓塞
老年人与中青年
危险分层
治疗策略
预后
pulmonary thromboembolism
young and elderly patients
risk stratification
treatment
prognosis
