摘要
目的探讨缺血性脑血管病血管搭桥治疗中CT灌注的应用价值。方法对2组实施搭桥手术的缺血性脑血管病患者在手术前后进行CT灌注检查,再对手术前后的结果进行统计学分析。结果手术前2组患者绝大多数都存在着手术侧脑血流量(CBF)和脑血容量(CBV)降低,达峰时间(TTP)延长情况,符合搭桥手术指征。手术后2组患者相对脑血流量(rCBF)均显著升高,显示了搭桥手术对这2组患者缺血区局脑血流灌注的改善效果显著;其中烟雾病组相对脑血容量(rCBV)较手术前升高,而非烟雾病搭桥组rCBV与术前变化不明显;烟雾病组相对达峰时间(rTTP)较手术前缩短,非烟雾病组rTTP改变不明显。结论 CT灌注对局部脑血流的评价结果是缺血性脑血管病外科治疗前的重要手术指证;CT灌注对于缺血性脑血管病外科治疗后的疗效评估很有价值。
Objective To investigate the application of CF peffusion in the bypass surgery for ischemic cerebrovascular diseases. Methods CT perfnsion imaging was performed in the patients of two groups before and af- ter operation, who accepted bypass surgery for isehemic cerebrovascular disease. The final results were analyzed by statistics. Results The cerebral blood flow （CBF） and cerebral blood volume （CBV） in the affected side of most patients in two groups were decreased and time to peak （TIP） prolonged before treatment, which was consistent with indication of bypass operation. Postoperative relative cerebral blood flow （rCBF） of all patients were improved obviously, which indicated the significant effect of bypass in improving the cerebral blood flow in ischemic region; postoperative relative cerebral blood volume （rCBV） of moyamoya group was higher than that of preoperation, but the diversity of rCBV in non-moyamoya group was not obvious; postoperative relative time to peak （rTTP）of moyamoya group was shorter than that of preoperation, but the diversity of rTIP of non-moyamoya group was not obvious. Conclusion The results of CT perfnsion are the important indication of surgical treatment for ischemic cerebrovascular diseases; CT peffusion is valuable in evaluating therapeutic effect of surgical treatment for ischemic cerebrovascular diseases.
出处
《中华神经外科疾病研究杂志》
CAS
2014年第1期43-46,共4页
Chinese Journal of Neurosurgical Disease Research
基金
上海市科学技术委员会科研基金资助项目(074119504)
关键词
CT灌注
缺血性脑血管病
血管搭桥
CT perfnsion
Ischemic cerebrovascular disease
Bypass surgery
