摘要
目的 探讨心肌血流储备分数（FFR）处于临界值（0.75～0.80）时应用不同的治疗策略对生活质量的影响.方法 对60例冠状动脉造影显示冠状动脉病变（狭窄70%～75%） 并且FFR处于临界值的冠心病患者随机分为经皮冠状动脉介入治疗组（PCI组,n=30）和药物治疗组（保守组,n=30）进行治疗,平均随访6个月,观察两组主要不良心血管事件（MACE）和西雅图心绞痛量表（SAQ）情况.结果 PCI组和保守组对MACE和SAQ的影响差异无统计学意义（P＞0.05）.结论 狭窄程度达70%～75%的冠状动脉病变若FFR处于临界值（0.75～0.80）,仍可安全地给予药物保守治疗.
Objective To evaluate the effect of different treatment strategies on life quality in patients with myocardial fractional flow reserve （FFRmyo） at critical point （0.75 -0.80）. Methods Sixty coronary artery disease （CAD） patients with 70 -75% coronary artery stenosis on angiography and FFRmyo at critical point （0.75-0.80） were randomized into two groups：30 patients underwent coronary artery stenting （PCI group）, and 30 patients received pure drug therapy. Patients were followed up to 6 months. Major adverse cardiac events （MACE） and Seattle angina questionaire （SAQ） were primary endpoints. Results Differences in MACE incidence and SAQ scores between two groups were not significant （ P 〉 0.05）. Conclusion Pure drug therapy can be used in patients with lesion of 70% - 75% stenosis and FFRmyo at critical point （0.75-0.80）.
出处
《微创医学》
2013年第6期678-680,共3页
Journal of Minimally Invasive Medicine
