摘要
目的:观察壮医药线点灸治疗对类风湿关节炎(RA)血清肿瘤坏死因子α及白细胞介素1β的影响,探讨其治疗机制。方法:选取活动性类风湿关节炎90例,随机分为药线治疗组30例,空白线灸组30例,西药对照组30例,药线治疗组和空白线灸组分别采用壮医药线、空白苎麻线点灸,同时配合西药治疗,采用ELISA法检测治疗前后3组患者的血清TNF-α和IL-1β。结果:药线治疗组治疗后与治疗前比较TNF-α、IL-1β有显著性差异(P<0.01),药线治疗组治疗后TNF-α、IL-1β较空白线灸组和西药对照组治疗后也有明显降低(P<0.05)。结论:壮医药线点灸治疗可降低RA患者的血清TNF-α、IL-1β水平,这是其可能的治疗机制。
Objective：To observe the intluence of the medicated thread moxibustion of Zhuang medicine on tumor necrosis factor alpha and interleukin- 1 beta in rheumatoid arthritis （RA） serum,exploring the treatment mechanism. Methods：90 eases of active rheumatoid arthritis were randomly divided into medicated thread treatment group, blank thread moxibustion group and western medicine eontrol group,30 cases for each group. The medicated thread treatment group and blank thread moxibustion group respectively used the medicated thread of Zhuang medieine and ramie line to moxibustion,at the same time cooperated with western medicine treatment in each group. ELISA method was used to detect se rum TNF - α and IL - 1 β in the three groups before and after treatment. Results ： TNF - α and IL - 1β in medicated thread treatment group had a significant difference before and after treatment （ P 〈 0.01 ）. Compared with blank thread moxibustion group and western medicine control group,TNF - α and IL - 1β in medicated thread treatment group reduced significantly （P 〈 0. 05 ）. Conclusions ： Treatment of the medicated thread moxibustion of Zhuang medicine can reduce the levels of TNF - α and IL - 1β in RA patients serum, and this is the possible mechanism of the treatment.
出处
《中华中医药学刊》
CAS
2014年第2期332-334,共3页
Chinese Archives of Traditional Chinese Medicine
基金
广西自然科学基金面上项目(2010GXNSFA013258)
柳州市科技局科技攻关项目(2009021519)
关键词
壮医药线点灸
类风湿关节炎
肿瘤坏死因子Α
白细胞介素1Β
medicated thread moxibustion of Zhuang medicine
rheumatoid arthritis
tumor necrosis factor alpha
Interleukin - 1 beta
