摘要
目的:探讨欣普贝生和催产素在足月引产中的应用效果。方法:收治足月引产产妇80例,随机分成对照组和观察组各40例。观察组给予普贝生10mg塞阴道引产;对照组给予催产素2.5U加入5%葡萄糖溶液500ml中静滴引产,观察比较两组宫颈评分的变化、引产成功率、临产时间、剖宫产率和对新生儿的影响。结果:观察组产妇用药后宫颈评分明显高于对照组,24小时引产成功率90%。对照组24小时引产成功率60.0%,两组比较差异有统计学意义(P<0.05)。欣普贝生的不良反应为子宫过度刺激,发生率为5%,但发生率低,将药取出后好转。结论:欣普贝生是一种安全、有效的促宫颈成熟药物。
Objective：To explore the effect of suppositories and oxytocin application in induced term labor.Methods：We selected 80 cases of maternal induced term labor in 2012 September to 2013 October.These pa-tients were randomly divided into the obser-vation group and the control group with 40 cases in each.Methods：The observation group was given 10mg propess into the vagi-na to induce labor.Continuous intravenous drip of 2.5U oxytocin with 5% glucose solu-tion 500ml of the control group to induce la-bor.We observed index of the two groups, such as cervical score,the successful rate of induced labor,labor time,the rate of cesarean section and the effect of cesarean section to neonatal.Results：The observation group of cervical score was significantly higher than control group.The successful rate of induced labor in 24 hours of observation group is 90% and control group is 60.0%.The differ-ence between the two groups was signifi-cant（P〈 0.05）.The adverse reaction of propess was uterine hyperstimulation and the incidence rate was 5% .If we take the medicine out,the adverse reaction will be better.Conclusion：Propess is a safe,effective agent in promoting cervical ripening.
关键词
足月引产
欣普贝生
缩宫素
应用效果
Induced term labor
Propess
Oxytocin
The application effect
