摘要
Notch、Wnt和Hh信号通路均参与了三阴性乳腺癌的发生发展。Aurora激酶A、Chk1、miR-93等在三阴性乳腺癌中存在过表达,并与其预后相关,为其治疗提供了新靶点。
Abstract : Note.h, Wnt,Hh signaling pathways parlieipate in the development of triple-negative breast caner: Aurcra Kinase A ,Chkl ,miR-93 are over-expressed and correlated with prog nosis in triple-negative breast cancer,they may provide more potential therapeutie targets.
出处
《中国肿瘤》
CAS
2014年第1期53-57,共5页
China Cancer
关键词
三阴性
乳腺癌
信号通路
靶向治疗
triple-negative phenotype
breast cancer
signal pathway
targeted therapy