摘要
目的探讨妇科肿瘤患者化疗后不良反应的类型、临床表现和治疗情况,以期提高临床诊治水平。方法随机选择2011年2月至2013年4月接受化疗,并同时出现不同程度药物不良反应的妇科肿瘤患者115例,通过回顾性分析,探讨不良反应的类型、临床表现和治疗转归。结果妇科肿瘤患者化疗后不良反应以涉及全身多脏器系统、皮肤及附件和消化系统为主,其他脏器系统不良反应发生率较为接近。经过治疗后,过敏性休克、骨髓抑制、心脏毒性、腹痛腹泻和呼吸系统损伤的治疗效果较好。结论妇科肿瘤患者化疗后可出现多种类型的不良反应,对症治疗和个体化治疗是预防不良反应的关键。
Objective To investigate the types ,clinical manifestations and therapy of chemotherapy adverse drug reactions in patients with gynecological caner ,in order to improve the clinical diagnosis and therapy .Methods From February 2011 to April 2013 ,115 cases of gynecological cancer patients with chemotherapy adverse drug reac-tions were randomly selected .Retrospective analysis was performed to study the types ,clinical manifestations and therapeutic turnover of chemotherapy adverse drug reaction .Results Multiple organs and systems ,skin and accesso-ries ,and digestive system were the main organs and systems involved in chemotherapy adverse drug reactions .After treatment ,anaphylactic shock ,bone marrow suppression ,cardiac toxicity ,abdominal pain and diarrhea ,and respirato-ry injuries were healed .Conclusion The types of chemotherapy adverse drug reactions could be various in patients with gynecological cancer .Symptomatic treatment and individual treatment might be important to prevent adverse re-actions .
出处
《检验医学与临床》
CAS
2014年第3期292-293,296,共3页
Laboratory Medicine and Clinic
基金
四川省卫生厅一般支持项目(项目编号SW-2010BNO.1018)
关键词
妇科肿瘤
化疗药物
不良反应
临床诊治
gynecologic oncology
chemotherapy drug
adverse reactions
clinical diagnosis and treat-ment
