摘要
目的 探讨丹红注射液联合阿托伐他汀治疗老年不稳定型心绞痛疗效.方法选择2010 年1 月～2013 年1月在我院住院治疗的不稳定性心绞痛患者60 例,随机分为观察组和对照组各30 例,对照组予常规对症治疗及阿托伐他汀20 mg/d 口服,晚睡前1 次顿服;观察组加用丹红注射液20 mL 加入生理盐水溶液250 mL,缓慢静脉滴注,每日1 次,疗程14 d.观察并比较两组的疗效及治疗前后心绞痛的发作频率、心脏事件及再次入院情况.结果 观察组显效16 例、有效12 例、无效2 例,其总有效率达93.3%.观察组临床总有效率明显高于对照组,组间比较,差异有统计学意义（χ2=6.328,P〈0.05）.两组治疗后心绞痛的发作频率比较,差异具有统计学意义（t=2.375,P＜0.05）.两组患者心脏事件及再次入院情况比较,差异有统计学意义（P〈0.05）.结论丹红注射液联合阿托伐他汀治疗老年不稳定型心绞痛疗效确切,可以明显改善患者的临床症状,减少心脏事件的发生,值得推广和应用.
Objective To investigate the effect of danhong injection combined with atorvastatin in treatment of elderly patients with unstable angina. Methods A total of 60 patients in our hospital with unstable angina from January 2010 to January 2013 were randomly divided into observation group and control group, each of 30 patients. The control group were given conventional symptomatic treatment and atorvastatin, observation group treated with danhong injection, treat- ment for 14 d. Before and after treatment of angina attack frequency, cardiac events and re-admissions were compared between two groups. Results There were 16 cases markedly effective, 12 cases effective, 2 cases ineffective, the total effective rate was 93.3%. The clinical total effective rate of treatment group was significantly higher than the control group（χ2=6.328,P〈0.05）. After treatment, angina attack frequency in two groups had significant difference（t=2.375, P〈 0.05）. Two groups of patients readmitted cardiac events and circumstances, the difference was statistically significant（P〈 0.05）. Conclusion Danhong injection combined with atorvastatin in treatment of elderly patients with unstable angina efficacy, can significantly improve the patient＇s clinical symptoms and reduce cardiac events, worthy of promotion and application.
出处
《中国现代医生》
2014年第3期41-42,45,共3页
China Modern Doctor
