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成釉细胞瘤中survivin和COX-2的表达及意义 被引量:4

Expression and significance of survivin and COX-2 in ameloblastoma
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摘要 免疫组织化学SP法检测发现survivin和COX-2蛋白在正常人口腔黏膜组织中的阳性率分别为18.18%(4/22)和36.36%(8/22),在成釉细胞瘤中的阳性率分别为71.67%(43/60)和81.67%(49/60),组间比较,P<0.001。成釉细胞瘤中survivin和COX-2蛋白的表达具有正相关性(r=0.529,P=0.000)。Survivin与COX-2可能参与成釉细胞瘤发生、发展过程。 Streptavidin-biotinperoxidase (SP)examination showed that survivin and COX-2 were expressed in 18. 18% (4/22) and 36.36% (8/22) cases of normal oral mueosa ( NOM), and in 71.67% (43/60) and 81.67 % (49/60) cases of ameloblastoma ( AB ), re- spectively (between 2 groups, P 〈 0.001 ). The expression of survivin and COX-2 in AB was positively correlated( r =0.529, P = 0.000). Survivin and COX-2 may be involved in the development of AB.
出处 《实用口腔医学杂志》 CAS CSCD 北大核心 2014年第1期126-128,共3页 Journal of Practical Stomatology
关键词 成釉细胞瘤 SURVIVIN COX-2 免疫组织化学 Ameloblastoma Survivin COX- 2 Immunohistochemistry
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参考文献8

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