摘要
目的评价宫颈环扎治疗前置胎盘的效果。方法于2012年3月在中国医科大学图书馆计算机检索PubMed、EMbase、Cochrane Library、中国生物医学文献数据库和维普期刊数据库,并辅以手工检索,收集宫颈环扎治疗前置胎盘的随机对照试验或半随机对照试验,提取有效数据,采用stata 11软件进行Meta分析。结果共纳入9个研究,其中6个随机对照试验,3个半随机对照试验,共386例患者。Meta分析结果显示,与对照组相比,宫颈环扎组延长分娩的孕周[WMD=3.16,95%CI(1.37,4.95)],延长维持妊娠的天数[WMD=19.78,95%CI(12.99,26.56)],增加新生儿出生平均体重[WMD=635.84,95%CI(352.13,919.55)],减少输血的次数[RR=0.49,95%CI(0.32,0.76)],而随机分配后发生出血的人数[RR=0.55,95%CI(0.39,0.78)]、围产儿死亡数[RR=0.17,95%CI(0.08,0.35)]、新生儿呼吸窘迫综合征发生率[RR=0.41,95%CI(0.20,0.85)]明显少于对照组,差异均具有统计学意义。结论 Meta分析表明,宫颈环扎对前置胎盘治疗有效。
Objective To evaluate the effect of the treatment that cervical cerclage deal with placenta previa. Methods Randomized controlled trials （RCTs） or quasi-randomized controlled trial（quasi-RCT） involving cervical cerclage in the treatment of placenta previa were searched and identified from PubMed, EMBASE, Cochrane Library, CBM and VIP in the China Medical University library during March 2012. We also hand searched relevant journals. Extract the valid data and Meta-analyses were conducted by stata 11 software. Results We included nine trials, six RCT, three quasi-RCT, a total of 386 cases. Meta-analyses showed that there were significant differences between cervical cerclage and control in the average gestational age birth [WMD = 3.16,95% CI（ 1.37,4. 95）] ,maintain the number of days of pregnancy [ WMD = 19. 78,95 % CI （ 12. 99,26. 56 ） ], the average birth weight [ WMD = 635.84,95 % CI （352. 13,919. 55 ） ], the number of blood transfusion [ RR = 0.49,95% CI （ O. 32,0.76 ） ], the number of bleeding [ RR = 0. 55,95% CI （0. 39,0. 78 ） ], perinatal mortality [ RR = O. 17,95 % CI （0. 08,0. 35 ） ] and the incidence of neonatal respiratory distress syndrome[ RR =0. 41,95% CI（0. 20,0. 85 ） ]. Conclusion Meta-analysis suggests that cervical cerclage significantly benefits placenta previa.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2014年第2期131-135,共5页
Chinese Journal of Practical Gynecology and Obstetrics
