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妊娠期亚临床甲状腺功能减低与妊娠结局分析 被引量:8

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摘要 目的探讨妊娠期亚临床甲状腺功能减低对妊娠结局和产科并发症的影响。方法用化学发光法检测血清游离甲状腺素(FT4)、促甲状腺激素(TSH)、甲状腺过氧化物酶抗体(TPOAb)浓度,对达到亚临床甲减诊断标准者,按TPOAb阴性或阳性结果进行分组研究,随访妊娠结局。结果筛查1 279名孕妇,临床甲减(13例)发生率为1.02%,亚临床甲减(57例)发生率为4.46%。亚临床甲减发生流产、早产、胎儿生长受限(FGR)、妊娠高血压疾病、妊娠期糖尿病、贫血及胎盘早剥等产科并发症风险增加,不良妊娠结局发生率达40.35%(25/57),正常对照组为18%。结论妊娠期亚临床甲状腺功能减退与妊娠不良结局及并发症有相关性。对孕妇人群进行甲状腺功能筛查,及时、适当的治疗可将妊娠风险降低。
出处 《宁夏医学杂志》 CAS 2014年第1期62-64,共3页 Ningxia Medical Journal
基金 宁夏银川市科技局科技计划项目(2060402)
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