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艾灸抑制肠腑病内脏痛的效应及机制研究 被引量:14

Study on effect and mechanism of moxibustion inhibit visceral pain of intestinal disease
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摘要 本课题组对艾灸疗法在肠腑病内脏痛中镇痛实践进行了探索,开展了艾灸治疗溃疡性结肠炎、克罗恩病、肠易激综合征的临床实践,结果显示艾灸对溃疡性结肠炎、克罗恩病、肠易激综合征患者腹痛症状具有良好的镇痛效应;并从抑制肠道炎性反应、促进病变局部组织修复和/或功能改善、提高痛阈及调节中枢/病变局部神经介质等疼痛相关物质水平等方面分别阐释了艾灸在不同类型的肠腑病内脏痛中镇痛的作用机制,并对今后艾灸镇痛在肠腑病中的应用与研究发展趋势进行思考和展望。 In this study, the practice of moxibustion analgesia on intestinal pain diseases was explored. Moxibustion treatment in clinical practice demonstrated a positive analgesic effect on ulcerative colitis, Crohn's disease and irritable bowel syndrome patients with abdominal pain. The principle of moxibustion analgesia on different types of intestinal pain disorders was also developed, with respect to inhibiting intestinal inflammatory response, promoting local lesion tissue repair and/or improving its function, increasing the pain threshold and regulating the level of pain related substance including central/local lesion neuromediator, et al. This study also addressed the development of application and research of moxibustion analgesia on intestinal diseases in the future.
出处 《中华中医药杂志》 CAS CSCD 北大核心 2014年第2期419-422,共4页 China Journal of Traditional Chinese Medicine and Pharmacy
基金 国家重点基础研究发展计划(973计划)(N o.2009C B522900) 国家自然科学基金项目(No.30973783) 上海市科委项目资助(No.11ZR1434300) 上海市卫生局项目资助(No.2009209)~~
关键词 肠腑病 内脏痛 艾灸 镇痛 Intestinal disease Visceral pain Moxibustion Analgesia
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