摘要
文中综述了昆虫对苏云金杆菌 ( Bt)毒素产生抗性的生化遗传机理及抗性的遗传及交叉抗性情况。昆虫对 Bt毒素的抗性可能在 6个环节发生 ,其中与毒素特异结合的受体上结合位点的改变及毒素水解过程的变化是抗性产生的两个主要环节。从现有研究结果来看 ,实验室及田间抗性昆虫品系对 Bt毒素产生的抗性主要与昆虫中肠上皮细胞膜上 Bt毒素特异结合受体的变化有关。深入研究昆虫对 Bt毒素的抗性机理 ,将有助于建立抗性的早期监测技术、抗性治理措施 ,实现无公害 Bt农药及转
The current knowledge of biochemical and genetic mechanisms of insect resistance to Bacillus thuringiensis toxin is reviewed. Six potential steps concerning the occurrence of resistance are suggested. Available information on resistance inheritance and cross-resistance is provided. Binding site modification and altered proteolytic processing are involved in most cases of resistance. From the available information it seems that binding site modification is the most significant resistance mechanism in the field and laboratory resistant strains. Studying the mechanism of insect resistance to Bacillus thuringiensis toxin will provide more toxin selection, wider utilization, and longer durability in integrated pest management programs that utilize Bt toxin and Bt crops.
出处
《昆虫知识》
CSCD
北大核心
2001年第1期12-17,共6页
Entomological Knowledge
基金
瑞典国际科学基金IFS-C/2366-2
农业虫鼠害综合治理研究国家重点实验室开放研究基金-9915项目资助
关键词
苏云金杆菌
抗性
机理
结合位点
水解过程
Bacillus thuringiensis
resistance
mechanism
binding site
proteolytic processing
