摘要
目的探讨冠心病(CHD)患者血清同型半胱氨酸(HCY)和C反应蛋白(CRP)的水平变化及临床意义。方法选择经冠状动脉造影检查确诊为CHD的门诊及住院患者105例作为观察对象,其中包括稳定型心绞痛(SAP组)31例、不稳定型心绞痛(UAP组)39例、急性心肌梗死(AMI组)35例;并选择同期体检的健康人40例作为对照组。检测所有观察对象的血清HCY、CRP水平,并对检测结果进行统计学分析。结果 CHD组患者血清HCY和CRP水平均显著高于对照组,差异有统计学意义(P<0.05);CHD患者各组之间血清HCY、CRP水平亦存在显著差异(P<0.05)。结论 CHD患者血清HCY和CRP水平与冠状动脉病变程度相关,对CHD的临床诊断及疗效监测有重要价值。
Objective To investigate the clinical significance of Hcy and CRP levels in serum lor patients with coronary heart disease（CHD）. Methods 105 patients with CHD were divided into stable angina pectoris （SAP） group （ n = 31 ）, unstable angina pectoris （UAP） group （ n = 39） and acute myocardial infarction （AMI） group（ n =35） according to clinical diagnosis, 40 healthy person were employed as control. The levels of Hcy and CRP in serum of them were detected. Results The HCY and CRP levels of CHD patients were significantly higher than those of control （P 〈 0.01 ）. The Hcy and CRP levels of three CHD groups present significant difference, （AMI group 〉 UAP group 〉 SAP group）. Conclusions HCY and CRP levels in serum of CHD patients are related to severity of the disease, and deteetion of HCY and CRP levels in serum has important clinical value on the diagnosis and therapeutic effect monitoring for CHD.
出处
《齐齐哈尔医学院学报》
2013年第23期3445-3446,共2页
Journal of Qiqihar Medical University
关键词
冠心病
同型半胱氨酸
C反应蛋白
Coronary heart disease
Homocysteine
C-reactive protein
