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不同分期CKD患者甲状腺激素异常的临床研究 被引量:1

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摘要 目的观察慢性肾脏病(CKD)不同分期患者血清甲状腺激素水平变化及其临床意义。方法对279例CKD患者进行分期,抽取空腹血标本检测其总甲状腺素(T4)、三碘甲状腺原氨酸(T3)、促甲状腺激素(TSH)等指标,观察其变化。采用SPSS 13.0软件进行统计学分析。结果不同CKD患者的T3、T4、TSH有显著性差异,且T3、T4随着分期的变化(CKD1→CKD5),值跟着相应的变小,呈现负性线性趋势特征。TSH值随着分期的变化(CKD1→CKD5),值跟着相应的变大,呈现正性线性趋势特征。BUN与T3、T4均具有显著相关性,BUN与TSH则没有显著的相关性(P>0.05)。GFR与T3、T4,TSH均具有显著相关性,非透析组和透析组比较的t检验结果 :两组的T3、T4、TSH值则没有显著差异(P>0.05)。结论肾功能减退与甲状腺激素的改变关系明显,藉此可从一定意义上判断病情的严重程度和预后。
出处 《中国医学工程》 2013年第12期46-46,48,共2页 China Medical Engineering
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